General Information

Product

CD56 / NCAM Antibody

Description

Affinity Purified Neural Cell Adhesion Molecule 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 800-847 on human neural cell adhesion molecule 1.

Accession #

GenBank: EAW67208.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

UPI0000EE39A0

Overview

Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane.

Molecular Function

Developmental protein; Cell adhesion; Differentiation; Neurogenesis

Subcellular Location

Cell membrane; Single-pass type I membrane protein

Expression

Expressed in the fetal and adult brain as well as in Schwann cell culture. Also detected in adult peripheral tissues.

Alternative Nomenclature

antigen MSK39 identified by monoclonal antibody 5.1H11 antibody

antigen recognized by monoclonal antibody 5.1H11 antibody

CD 56 antibody

CD56 antigen antibody

Cell Adhesion Molecule Neural 1 antibody

MSK39 antibody

N CAM 180 antibody

N-CAM-1 antibody

NCAM 120 antibody

NCAM 140 antibody

NCAM antibody

NCAMC antibody

NCAM1 antibody

Neural cell adhesion molecule 1 antibody

Neural cell adhesion molecule NCAM antibody

General Information

Product

CD47 Antibody

Description

Affinity Purified Leukocyte surface antigen CD47 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse

Predicted: Rat

Immunogen

Synthetic peptide taken within amino acid region 100-150 on human CD47 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q08722 

Overview

Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.

Molecular Function

Thrombospondin receptor activity; Cell adhesion

Subcellular Location

Cell membrane, Membrane

Expression

Very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain.

Structure

Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Alternative Nomenclature

Antigen identified by monoclonal antibody 1D8 antibody

Antigenic surface determinant protein OA3 antibody

CD47 antigen (Rh-related antigen, integrin-associated signal transducer) antibody

CD47 glycoprotein antibody

CD47 molecule antibody

IAP antibody

Integrin Associated Protein antibody

Integrin associated signal transducer antibody

Leukocyte surface antigen CD47 antibody

MER6 antibody

OA3 antibody

Protein MER6 antibody

Rh related antigen antibody

General Information

Product

CD45 Antibody

Description

Affinity Purified Receptor-type tyrosine-protein phosphatase C Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 1100-1150 on human Receptor-type tyrosine-protein phosphatase C.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500-1:5,000

Protein

Uniprot #

P08575

Subcellular Location

Cell membrane, Membrane

Structure

Repeat, Signal, Transmembrane, Transmembrane helix

Alternative Nomenclature

B220 antibody
CD45 antigen antibody
CD45R antibody
GP180 antibody
LCA antibody
Leukocyte common antigen antibody
loc antibody
Ly-5 antibody
LY5 antibody
Lyt-4 antibody
Protein tyrosine phosphatase receptor type c polypeptide antibody
Ptprc antibody
Receptor-type tyrosine-protein phosphatase C antibody
T200 antibody
T200 glycoprotein antibody
T200 leukocyte common antigen antibody