ELOVL1 Antibody

Product no.: ELOVL1-101AP

$285.00

Description

General Information
Product	ELOVL1 Antibody
Description	Affinity Purified Elongation of very long chain fatty acids protein 1 Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Monkey Predicted: Mouse
Immunogen	Synthetic peptide taken within amino acid region 148-198 on human Elongation of very long chain fatty acids protein 1.
Accession #	NCBI: NP_001243331
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5 µg/µl in antibody stabilization buffer
Immunoglobulin	IgG
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
ELISA	1:10,000
Immunohistochemistry	1:100
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	Q9BW60
Overview	Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
Molecular Function	Transferase; Fatty acid biosynthesis & metabolism; Lipid biosynthesis & metabolism
Subcellular Location	Endoplasmic reticulum membrane; Multi-pass membrane protein
Expression	Ubiquitous
Structure	The di-lysine motif may confer endoplasmic reticulum localization.
Alternative Nomenclature	3 keto acyl CoA synthase ELOVL1 antibody CGI 88 antibody Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 1 antibody Elongation of very long chain fatty acids protein 1 antibody ELOVL 1 antibody ELOVL FA elongase 1 antibody ELOVL fatty acid elongase 1 antibody ELOVL1 antibody Ssc1 antibody Very-long-chain 3-oxoacyl-CoA synthase 1 antibody

Protein information supplied by UniProt