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General Information
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Product
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FOLR2 Antibody FITC
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Description
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FITC-Conjugated Folate receptor beta Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 1-50 on rat Folate receptor 2 protein.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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FITC-Conjugated
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Purification Method
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Immobilized antigen affinity chromatography
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:50,000
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| Immunohistochemistry |
1:50-1:150 |
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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D4A4S5
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Overview
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Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.
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Molecular Function
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Receptor
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Subcellular Location
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Cell membrane; Lipidanchor > GPI-anchor, Secreted
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Expression
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Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues.
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Structure
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Belongs to the folate receptor family.
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Alternative Nomenclature
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beta hFR antibody
FBP antibody
FBP/PL 1 antibody
FBP2 antibody
fetal/placental antibody
folate receptor 2 (fetal) antibody
Folate receptor 2 antibody
Folate receptor antibody
Folate receptor beta antibody
Folate receptor, fetal/placental antibody
Folbp 2 antibody
Folr2 antibody
FR beta antibody
FR P3 antibody
Placental folate binding protein antibody
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FOLR2 Antibody
FOLR2 Antibody BIOTIN
FOLR2 Blocking Peptide
FOLR2 Positive Control
