FOLR2 Positive Control

General Information

Product

FOLR2 Positive Control

Description

Western Blot Positive Control Folate receptor beta Antibody

Verified Applications

WB

Immunogen

Purified protein.

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

D4A4S5

Overview

Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.

Molecular Function

Receptor

Subcellular Location

Cell membrane; Lipidanchor > GPI-anchor, Secreted

Expression

Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues.

Structure

Belongs to the folate receptor family.

Alternative Nomenclature

beta hFR antibody
FBP antibody
FBP/PL 1 antibody
FBP2 antibody
fetal/placental antibody
folate receptor 2 (fetal) antibody
Folate receptor 2 antibody
Folate receptor antibody
Folate receptor beta antibody
Folate receptor, fetal/placental antibody
Folbp 2 antibody
Folr2 antibody
FR beta antibody
FR P3 antibody
Placental folate binding protein antibody