GADD34 Antibody

Product no.: GADD34-101AP
$295.00
$265.00


General Information

 

 

Product

 

GADD34 Antibody

Description

Affinity Purified Growth arrest and DNA damage-inducible protein GADD34 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Predicted: Bovine, Monkey

Immunogen

Synthetic peptide corresponding to internal sequence of amino acids 380-400 of Human GADD34, covalently modified and coupled to a carrier protein.

 

Sequence:

PATGVFLKSWVYQPGEDTEEE


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.58 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

 

DB

1:800-1:1,000

ELISA

1:800-1:1,000

Immunohistochemistry 1:50-1:150
Immunoprecipitation 1:200

Western Blot

1:500


Protein

 

 

Uniprot #

 

O75807

Overview

Recruits serine/threonine-protein phosphatase PP1 to dephosphorylate translation initation factor eIF2A/EIF2S1.  This reverses shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress.

Molecular Function

Apoptosis; Stress Response; Translation regulation

Subcellular Location

Endoplasmic Reticulum membrane; Peripheral membrane protein; Cytoplasmic side; Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic Side

Expression

induced by methyl methanesulfonate and ionizing irradiation.  Apoptosis is induced by interluekin 24 in melanoma cells

Structure

belongs to PPP1R15 family.

Alternative Nomenclature

Apoptosis associated protein antibody

GADD 34 antibody

Growth arrest and DNA-damage-inducible 34 antibody

Myeloid differentiation primary response protein MyD116 homolog antibody

PPP1R15A antibody

Protein phosphatase 1 regulatory (inhibitor) subunit 15A antibody

Protein information supplied by UniProt
 

 

Accessories

Product Note Status Price
GADD34 Antibody FITC GADD34 Antibody FITC
GADD34-FITC $350.00 *
GADD34 Antibody BIOTIN GADD34 Antibody BIOTIN
GADD34-BIOTIN $350.00 *
GADD34 Blocking Peptide GADD34 Blocking Peptide
P-GADD34 $145.00 *
GADD34 Positive Control GADD34 Positive Control
PC-GADD34 $185.00 *
Display accessory details

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GADD-101AP

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