GADD34 Antibody

Product no.: GADD34-101AP

$285.00

Description

General Information
Product	GADD34 Antibody
Description	Affinity Purified Growth arrest and DNA damage-inducible protein GADD34 Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat Predicted: Bovine, Monkey
Immunogen	Synthetic peptide corresponding to internal sequence of amino acids 380-400 of Human GADD34, covalently modified and coupled to a carrier protein. Sequence: PATGVFLKSWVYQPGEDTEEE
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.58 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
DB	1:800-1:1,000
ELISA	1:800-1:1,000
Immunohistochemistry	1:50-1:150
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	O75807
Overview	Recruits serine/threonine-protein phosphatase PP1 to dephosphorylate translation initation factor eIF2A/EIF2S1. This reverses shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress.
Molecular Function	Apoptosis; Stress Response; Translation regulation
Subcellular Location	Endoplasmic Reticulum membrane; Peripheral membrane protein; Cytoplasmic side; Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic Side
Expression	induced by methyl methanesulfonate and ionizing irradiation. Apoptosis is induced by interluekin 24 in melanoma cells
Structure	belongs to PPP1R15 family.
Alternative Nomenclature	Apoptosis associated protein antibody GADD 34 antibody Growth arrest and DNA-damage-inducible 34 antibody Myeloid differentiation primary response protein MyD116 homolog antibody PPP1R15A antibody Protein phosphatase 1 regulatory (inhibitor) subunit 15A antibody

Protein information supplied by UniProt