General Information |
|
Product |
LAT2 / NTAL Antibody FITC-Conjugated |
Description |
FITC-Conjugated Linker for activation of T-cells family member 2 Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Monkey |
Immunogen |
Synthetic peptide taken within amino acid region 40-90 on LAT2 protein. |
Accession # |
NCBI: NP_115852 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.54-0.72 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunohistochemistry | 1:100 |
Immunoprecipitation | 1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. |
Molecular Function |
SH2 domain binding |
Subcellular Location |
Cell membrane; Single-pass type III membrane protein |
Expression |
Highly expressed in spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. Also expressed in placenta, lung, pancreas and small intestine. Present in B-cells, NK cells and monocytes. Absent from T-cells (at protein level). |
Structure |
When phosphorylated, interacts with GRB2. May also interact with SOS1, GAB1 and CBL. |
Alternative Nomenclature |
HSPC046 antibody LAB antibody LAT2 antibody Linker for activation of B cells antibody Membrane associated adapter molecule antibody Non T cell activation linker antibody WBSCR 5 antibody Wbscr15 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
LAT2-201AP | |||
|
P-LAT2 | |||
|
LAT2-BIOTIN | |||
|
PC-LAT2 | |||
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