General Information |
|
Product |
MC4 Receptor Antibody FITC-Conjugated |
Description |
FITC-Conjugated Melanocortin receptor 4 Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 10-60 on human MC4R protein. |
Accession # |
NCBI: NP_005903.2 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.55-0.75 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunohistochemistry | 1:100 |
Immunoprecipitation | 1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). |
Molecular Function |
Melanocortin receptor activity, melanocyte-stimulating hormone receptor activity, neuropeptide binding, ubiquitin protein ligase binding |
Subcellular Location |
cell membrane, multi-pass membrane protein, membrane raft. (Note: Localizes to membrane rafts but is also loated in the cell membrane outside of these regions where channel response to cold is enhanced compared to membrane rafts) |
Expression |
Brain, placental, and gut tissues. |
Alternative Nomenclature |
MC4 R antibody Melanocortin receptor 4 antibody MGC126851 antibody MGC138197 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
MC4R-401AP | |||
|
P-MC4R | |||
|
MC4R-BIOTIN | |||
|
PC-MC4R | |||
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