General Information |
|
Product |
CD47 Peptide |
Description |
Antigenic Blocking Peptide Leukocyte surface antigen CD47 Antibody |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic peptide taken within amino acid region 100-150 on human CD47 protein. |
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|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
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Competition/Depletion assay |
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Uniprot # |
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Overview |
Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. |
Molecular Function |
Thrombospondin receptor activity; Cell adhesion |
Subcellular Location |
Cell membrane, Membrane |
Expression |
Very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. |
Structure |
Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
Alternative Nomenclature |
Antigen identified by monoclonal antibody 1D8 antibody Antigenic surface determinant protein OA3 antibody CD47 antigen (Rh-related antigen, integrin-associated signal transducer) antibody CD47 glycoprotein antibody CD47 molecule antibody IAP antibody Integrin Associated Protein antibody Integrin associated signal transducer antibody Leukocyte surface antigen CD47 antibody MER6 antibody OA3 antibody Protein MER6 antibody Rh related antigen antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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CD47-101AP | |||
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CD47-BIOTIN | |||
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CD47-FITC | |||
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PC-CD47 | |||
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