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General Information
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Product
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PARD6B Peptide
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Description
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Antigenic Blocking Peptide Partitioning Defective 6 homolog beta Antibody C-epitope
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide description
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Synthetic peptide corresponding to amino acids within region 340- 372 on human Partitioning Defective 6 homolog beta.
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Determinant
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C-epitope
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Storage
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-20?C for long term storage
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Application Protocol
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Immunodepletion, Immunocompetition
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q9BYG5
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Overview
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Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
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Molecular Function
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protein kinase C binding
Rho GTPase binding
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Subcellular Location
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Cell membrane, Cytoplasm
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Expression
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Expressed in pancreas and in both adult and fetal kidney. Weakly expressed in placenta and lung. Not expressed in other tissues.
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Structure
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The pseudo-CRIB domain together with the PDZ domain is required for the interaction with Rho small GTPases.
The PDZ domain mediates interaction with MPP5.
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Alternative Nomenclature
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OTTHUMP00000031269 antibody
PAR 6 beta antibody
Par 6 partitioning defective 6 homolog beta (C. elegans) antibody
PAR6B antibody
PARD6 beta antibody
PARD6B antibody
partitioning defective 6 homolog beta antibody
partitioning-defective protein 6, C. elegans, homolog of, beta antibody
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PARD6B Antibody
PARD6B Antibody BIOTIN
PARD6B Antibody FITC
PARD6B Positive Control
