PDE2A4 Blocking Peptide

General Information

Product

PDE2A4 Peptide

Description

Antigenic Blocking Peptide CGMP-stimulated phosphodiesterase 4 Antibody

Verified Applications

Immunodepletion/Competition Assay

Peptide Description

Synthetic peptide taken within amino acid region 1-50 on human PDE2A4 protein.

Accession #

GenBank: AAS75513.1

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

O00408

Overview

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.  Isoform PDE2A2: Regulates Mitochondrial cAMP Levels and Respiration.

Molecular Function

Hydrolase, calcium channel activity, cAMP binding

Subcellular Location

Isoform PDE2A3: Cell membrane; Lipid-anchor, Isoform PDE2A2: Mitochondrion matrix, Isoform PDE2A1: Cytoplasm, Isoform 5: Mitochondrion

Expression

Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.

Structure

Homodimer

Alternative Nomenclature

5''-cyclic phosphodiesterase antibody

cGMP dependent 3'5' cyclic phosphodiesterase antibody

cGMP stimulated phosphodiesterase 1 antibody

cGMP stimulated phosphodiesterase 4 antibody

cGMP-dependent 3'' antibody

CGS PDE antibody

Cyclic GMP stimulated phosphodiesterase antibody

Human cGMP stimulated 3'5' cyclic nucleotide phosphodiesterase antibody

PDE 2A antibody

PDE 2A4 antibody

Phosphodiesterase 2A cGMP stimulated antibody