General Information
|
|
Product
|
PDE2A4 Antibody FITC-Conjugated
|
Description
|
FITC-Conjugated CGMP-stimulated phosphodiesterase 4 Antibody
|
Verified Applications
|
ELISA, IP, WB
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Human, Mouse, Rat
|
Immunogen
|
Synthetic peptide taken within amino acid region 1-50 on human PDE2A4 protein.
|
Specificity |
This antibody will detect PDE2A4 only. |
Accession #
|
GenBank: AAS75513.1
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
0.5 µg/µl in antibody stabilization buffer
|
Form
|
FITC-Conjugated
|
Clonality
|
Polyclonal
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
DB
|
1:10,000
|
ELISA
|
1:10,000
|
Immunoprecipitation |
1:200 |
Western Blot
|
1:500
|
Protein
|
Uniprot #
|
O00408
|
Overview
|
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Isoform PDE2A2: Regulates Mitochondrial cAMP Levels and Respiration.
|
Molecular Function
|
Hydrolase, calcium channel activity, cAMP binding
|
Subcellular Location
|
Isoform PDE2A3: Cell membrane; Lipid-anchor, Isoform PDE2A2: Mitochondrion matrix, Isoform PDE2A1: Cytoplasm, Isoform 5: Mitochondrion
|
Expression
|
Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.
|
Structure
|
Homodimer
|
Alternative Nomenclature
|
5''-cyclic phosphodiesterase antibody
cGMP dependent 3'5' cyclic phosphodiesterase antibody
cGMP stimulated phosphodiesterase 1 antibody
cGMP stimulated phosphodiesterase 4 antibody
cGMP-dependent 3'' antibody
CGS PDE antibody
PDE 2A antibody
PDE 2A1 antibody
PDE 2A4 antibody
Phosphodiesterase 2A cGMP stimulated antibody
|
|
|