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General Information
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Product
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Phospho-PDE11A (S163) Peptide
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Description
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Antigenic Blocking Peptide Phosphorylated PDE11A (Serine 163) Antibody
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide description
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Synthetic peptide taken within amino acid region 100-200 on rat PDE11A protein. Phosphorylated Ser 163.
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Modification
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Phosphorylated
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Storage
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-20?C for long term storage
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Application Protocol
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Immunodepletion, Immunocompetition
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q8VID6
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Overview
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Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively (By similarity).
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Molecular Function
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3',5'-cyclic-AMP phosphodiesterase activity
3',5'-cyclic-GMP phosphodiesterase activity
3',5'-cyclic-nucleotide phosphodiesterase activity
cGMP binding Source: RGD
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
cyclic-nucleotide phosphod
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Expression
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Isoform 1 is expressed in brain, heart, kidney and liver, but not in prostate. Isoform 2 is specifically expressed in testis. Isoform 3 is expressed in various tissues including brain, lung, skeletal muscle, spleen, testis and prostate.
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Structure
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Belongs to the cyclic nucleotide phosphodiesterase family.
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Alternative Nomenclature
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5''-cyclic-AMP and -GMP phosphodiesterase 11A antibody
cAMP and cGMP cyclic nucleotide phosphodiesterase 11A antibody
cAMP and cGMP phosphodiesterase 11A antibody
cAMP phosphodiesterase 11A antibody
cGMP phosphodiesterase 11A antibody
Cyclic nucleotide phosphodiesterase 11A antibody
Dual 3'' antibody
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A antibody
FLJ23693 antibody
MGC133355 antibody
MGC133356 antibody
PDE 11A antibody
pde11 antibody
PDE11_HUMAN antibody
PDE11A antibody
PDE11A1 antibody
pde11a2 antibody
Phosphodiesterase 11A antibody
PPNAD2 antibody
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Phospho-PDE11A Antibody (S163) Antibody
Phospho-PDE11A (S163) Antibody BIOTIN
Phospho-PDE11A (S163) Antibody FITC
Phospho-PDE11A (S163) Positive Control
