Phospho-PDE11A (S163) Positive Control

General Information

Product

Phospho-PDE11A (S163) Positive Control

Description

Western Blot Positive Control Phosphorylated PDE11A (Serine 163) Antibody

Verified Applications

WB

Physical Properties

Quantity

5 Applications

Volume

Inquire

Concentration

The concentration of the sample is empirically set so that 20 µl per lane in Western and blotted with corresponding affinity purified antibody will give a clean band with a high signal to noise ratio on the gel.

Form

Western Blot Positive Control

Modification

Phosphorylated

Storage

-20?C for long term storage

Protein

Uniprot #

Q8VID6

Overview

Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively (By similarity).

Molecular Function

3',5'-cyclic-AMP phosphodiesterase activity

3',5'-cyclic-GMP phosphodiesterase activity

3',5'-cyclic-nucleotide phosphodiesterase activity

cGMP binding Source: RGD

cGMP-stimulated cyclic-nucleotide phosphodiesterase activity

cyclic-nucleotide phosphod

Expression

Isoform 1 is expressed in brain, heart, kidney and liver, but not in prostate. Isoform 2 is specifically expressed in testis. Isoform 3 is expressed in various tissues including brain, lung, skeletal muscle, spleen, testis and prostate.

Structure

Belongs to the cyclic nucleotide phosphodiesterase family.

Alternative Nomenclature

5''-cyclic-AMP and -GMP phosphodiesterase 11A antibody

cAMP and cGMP cyclic nucleotide phosphodiesterase 11A antibody

cAMP and cGMP phosphodiesterase 11A antibody

cAMP phosphodiesterase 11A antibody

cGMP phosphodiesterase 11A antibody

Cyclic nucleotide phosphodiesterase 11A antibody

Dual 3'' antibody

Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A antibody

FLJ23693 antibody

MGC133355 antibody

MGC133356 antibody

PDE 11A antibody

pde11 antibody

PDE11_HUMAN antibody

PDE11A antibody

PDE11A1 antibody

pde11a2 antibody

Phosphodiesterase 11A antibody

PPNAD2 antibody