Profilin Blocking Peptide

Product no.: P-PRFLN

$155.00

Description

General Information
Product	Profilin Peptide
Description	Antigenic Blocking Peptide Profilin 1 Antibody
Verified Applications	Immunodepletion, Immunocompetition
Peptide Description	Synthetic peptide corresponding to amino acids within region 50-100 on human Profilin 1.
Physical Properties
Quantity	250 µg
Volume	100 µl
Form	Antigenic Blocking Peptide
Purification Method	Immobilized antigen affinity chromatography
Storage	-20?C for long term storage
Application Protocol
Immunodepletion, Immunocompetition	Refer to competition assay protocol
Protein
Uniprot #	P07737
Overview	Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
Molecular Function	actin binding actin monomer binding adenyl-nucleotide exchange factor activity cadherin binding phosphatidylinositol-4,5-bisphosphate binding phosphotyrosine residue binding proline-rich region binding RNA binding
Subcellular Location	cytoskeleton
Expression	Expressed in epididymis (at protein level).
Structure	Actin binding protein antibody ALS18 antibody Epididymis tissue protein Li 184a antibody OTTHUMP00000125244 antibody PFN 1 antibody Pfn antibody PFN1 antibody PROF1_HUMAN antibody Profilin I antibody Profilin1 antibody
Alternative Nomenclature	Actin binding protein antibody ALS18 antibody Epididymis tissue protein Li 184a antibody OTTHUMP00000125244 antibody PFN 1 antibody Pfn antibody PFN1 antibody PROF1_HUMAN antibody Profilin I antibody Profilin-1 antibody Profilin1 antibody ProfilinI antibody

Protein information supplied by UniProt.