Profilin Positive Control

General Information

Product

Profilin Positive Control

Description

Western Blot Positive Control Profilin 1 Antibody

Verified Applications

WB

Physical Properties

Quantity

5 Applications

Volume

Inquire

Concentration

The concentration of the sample is empirically set so that 20 µl per lane in Western and blotted with corresponding affinity purified antibody will give a clean band with a high signal to noise ratio on the gel.

Form

Western Blot Positive Control

Storage

-20?C for long term storage

Protein

Uniprot #

P07737

Overview

Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.

Molecular Function

actin binding

actin monomer binding

adenyl-nucleotide exchange factor activity

cadherin binding

phosphatidylinositol-4,5-bisphosphate binding

phosphotyrosine residue binding

proline-rich region binding

RNA binding

Subcellular Location

cytoskeleton

Expression

Expressed in epididymis (at protein level).

Alternative Nomenclature

Actin binding protein antibody

ALS18 antibody

Epididymis tissue protein Li 184a antibody

OTTHUMP00000125244 antibody

PFN 1 antibody

Pfn antibody

PFN1 antibody

PROF1_HUMAN antibody

Profilin I antibody

Profilin1 antibody