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General Information
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Product
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SERINC5 Peptide
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Description
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Antigenic Blocking Peptide Serine incorporator 5
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 270-320 on human Serine incorporator 5 protein.
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Accession #
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NCBI: XP_011541606
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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UPI0005D01C8F
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Overview
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Restriction factor required to restrict infectivity of gammaretroviruses, such as HIV-1: acts by inhibiting early step of viral infection and impairing the ability of the viral particle to translocate its content to the cytoplasm (PubMed:26416733, PubMed:26416734). Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes.
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Molecular Function
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L-serine transmembrane transporter activity
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Subcellular Location
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Cell membrane; Multi-pass membrane
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Expression
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Highly expressed in placenta, skeletal muscle, spleen, thymus, testis and peripheral leukocyte and is expressed weakly in the heart, liver and fetal brain.
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Structure
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Belongs to the TDE1 family
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Alternative Nomenclature
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C5orf12 antibody
SERC5_HUMAN antibody
SERINC5 antibody
Serine incorporator 5 antibody
TPO1 antibody
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SERINC5 Positive Control
SERINC5 Antibody
SERINC5 Antibody BIOTIN
SERINC5 Antibody FITC
