|
General Information
|
|
|
Product
|
SERINC5 Positive Control
|
|
Description
|
Western Blot Positive Control Serine incorporator 5
|
|
Verified Applications
|
WB
|
|
Immunogen
|
Purified protein
|
|
Accession #
|
NCBI: XP_011541606
|
|
Physical Properties
|
|
|
Quantity
|
5 Applications
|
|
Volume
|
Inquire
|
|
Form
|
Western Blot Positive Control
|
|
Storage
|
-20⁰C for long term storage
|
|
Application Protocol
|
|
Western Blot
|
1:500
|
|
Protein
|
|
Uniprot #
|
UPI0005D01C8F
|
|
Overview
|
Restriction factor required to restrict infectivity of gammaretroviruses, such as HIV-1: acts by inhibiting early step of viral infection and impairing the ability of the viral particle to translocate its content to the cytoplasm (PubMed:26416733, PubMed:26416734). Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes (By similarity).
|
|
Molecular Function
|
L-serine transmembrane transporter activity
|
|
Subcellular Location
|
Cell membrane; Multi-pass membrane
|
|
Expression
|
Highly expressed in placenta, skeletal muscle, spleen, thymus, testis and peripheral leukocyte and is expressed weakly in the heart, liver and fetal brain.
|
|
Structure
|
Belongs to the TDE1 family
|
|
Alternative Nomenclature
|
C5orf12 antibody
SERC5_HUMAN antibody
SERINC5 antibody
Serine incorporator 5 antibody
TPO1 antibody
|
| |
|
SERINC5 Blocking Peptide
SERINC5 Antibody
SERINC5 Antibody BIOTIN
SERINC5 Antibody FITC
