General Information |
|
Product |
TLR5 Peptide |
Description |
Antigenic Blocking Peptide Toll-like receptor 5 |
Verified Applications |
Immunocompetition, Immunodepletion |
Peptide Description |
Synthetic peptide taken within amino acid region 195-225 on human TLR5 protein. |
|
|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
|
|
Competition/Depletion assay |
|
|
|
Uniprot # |
|
Overview |
Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
Molecular Function |
Receptor, interleukin-1 receptor binding, transmembrane signalling receptor activity |
Subcellular Location |
Membrane; Single-pass type I membrane protein |
Expression |
Highly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis. |
Structure |
Binds MYD88 via their respective TIR domains (By similarity). Homodimer both in the absence and presence of ligand. |
Alternative Nomenclature |
SLEB1 antibody TIL3 antibody Toll like receptor 5 antibody Toll/interleukin 1 receptor like protein 3 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
TLR-501AP | |||
|
TLR5-FITC | |||
|
TLR5-BIOTIN | |||
|
PC-TLR5 | |||
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