General Information |
|
Product |
FOLR1 Positive Control |
Description |
Western Blot Positive Control Folate receptor Alpha |
Verified Applications |
WB |
Immunogen |
Purified protein. |
|
|
Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
|
|
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation. Required for renal folate reabsorption. |
Molecular Function |
Receptor |
Subcellular Location |
Cell membrane, Cytoplasmic vesicle, Endosome, Membrane, Secreted |
Expression |
Detected in kidney proximal tubules. |
Structure |
Belongs to the folate receptor family. |
Alternative Nomenclature |
adult antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
FOLR1-101AP | |||
|
FOLR1-BIOTIN | |||
|
FOLR1-FITC | |||
|
P-FOLR1 | |||
Display accessory details |
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