General Information |
|
Product |
LAT2 / NTAL Positive Control |
Description |
Western Blot Positive Control Linker for activation of T-cells family member 2 |
Verified Applications |
WB |
Immunogen |
Purified Protein |
Accession # |
NCBI: NP_115852 |
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|
Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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|
Western Blot |
1:500 |
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Uniprot # |
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Overview |
Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. |
Molecular Function |
SH2 domain binding |
Subcellular Location |
Cell membrane; Single-pass type III membrane protein |
Expression |
Highly expressed in spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. Also expressed in placenta, lung, pancreas and small intestine. Present in B-cells, NK cells and monocytes. Absent from T-cells (at protein level). |
Structure |
When phosphorylated, interacts with GRB2. May also interact with SOS1, GAB1 and CBL. |
Alternative Nomenclature |
HSPC046 antibody LAB antibody LAT2 antibody Linker for activation of B cells antibody Membrane associated adapter molecule antibody Non T cell activation linker antibody WBSCR 5 antibody Wbscr15 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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LAT2-201AP | |||
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LAT2-FITC | |||
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P-LAT2 | |||
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LAT2-BIOTIN | |||
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