TLR1 Positive Control

General Information

Product

TLR1 Positive Control

Description

Western Blot Positive Control Toll-like receptor 1

Verified Applications

WB

Immunogen

Purified Protein

Accession #

NCBI:  NP_109607.1

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

Q9EPQ1

Overview

Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.

Molecular Function

Receptor, Transmembrane signaling receptor activity, triacyl lipopeptide binding

Subcellular Location

Cell membrane; Single-pass type I membrane protein, Cytoplasmic vesicle >  phagosome membrane; Single-pass type I membrane protein

Structure

Binds MYD88 (via TIR domains) (By similarity). Interacts (via extracellular domain) with TLR2. Ligand binding induces the formation of a heterodimer with TLR2 (By similarity). Interacts with CNPY3.

Alternative Nomenclature

CD281 antibody

CD281 antigen antibody

KIAA0012 antibody

LPRS5 antibody

rsc786 antibody

Similar to Drosophila Toll protein antibody

TIL antibody

TIL. LPRS5 antibody

Tlr1 antibody

Toll (Drosophila) homolog antibody

Toll like receptor 1 antibody

Toll like receptor 1 Precursor antibody

Toll/Interleukin 1 receptor like antibody

Toll/interleukin-1 receptor-like protein antibody