General Information |
|
Product |
REST / NRSF Antibody FITC-Conjugated |
Description |
FITC-Conjugated RE1-silencing transcription factor Antibody |
Verified Applications |
ELISA, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 1000-1097 on human REST protein. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.52-0.54 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunoprecipitation | 1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. |
Molecular Function |
Repressor, Chromatin binding, Core promoter binding |
Subcellular Location |
Nucleus |
Expression |
Ubiquitous, expressed at higher levels in the tissues of the lymphocytic compartment, including spleen, thymus, peripheral blood lymphocytes and ovaries. |
Structure |
Interacts with SIN3A, SIN3B and RCOR1. Interacts with CDYL. |
Alternative Nomenclature |
Neural Restrictive Silencer Factor antibody NRSF antibody RE1 silencing transcription factor antibody Repressor binding to the X2 box antibody REST antibody X2 box repressor antibody XBR antibody |
Protein information supplied by UniProt
To view the Specification Sheet for REST / NRSF Antibody, please click the link below:
Product | Note | Status | Price | |
---|---|---|---|---|
|
REST-101AP | |||
|
P-REST | |||
|
REST-BIOTIN | |||
|
PC-REST | |||
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