Septin 2 Antibody

General Information

Product

Septin 2 Antibody Affinity Purified

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 270-320 on human Septin-2 protein.

Accession #

Gen Bank:  AAH14455.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q15019

Overview

Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating effiecient vesicle transport, and by impeding MAP4 binding to tubulin. Required for progression through mitosis.

Molecular Function

Enzyme regulator activity

Subcellular Location

Cytoplasm, cytoskeleton, spindle, cleavage furrow, midbody, cell cortex, cilium membrane

Expression

Widely expressed. Up-regulated in liver cancer.

Alternative Nomenclature

DIFF6 antibody

KIAA0158 antibody

NEDD 5 antibody

Neural precursor cell expressed developmentally down regulated protein 5 antibody

Pnutl3 antibody

Protein NEDD5 antibody

septin 2 antibody