General Information |
|
Product |
TIA1 Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Nucleolysin TIA-1 isoform p40 Antibody |
Verified Applications |
CM, ELISA, ICC, IF, IHC, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 414-464 on human TIA1 protein. |
Accession # |
GenBank: BAD92448.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.55-0.75 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
Confocal Microscopy |
1:50 |
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunocytochemistry |
1:50 |
Immunofluorescence |
1:50 |
Immunohistochemistry |
1:50 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis. |
Molecular Function |
AU-rich element binding, nucleotide binding, poly(A) binding, poly (A) RNA binding |
Subcellular Location |
Cytoplasmic granule, nucleus. (Note: accumulates in cytoplasmic stress granules following cellular damage |
Alternative Nomenclature |
Cytotoxic granule associated RNA binding protein 1 antibody Nucleolysin TIA 1 isoform p40 antibody p40 TIA 1 antibody p40-TIA-1 (containing p15-TIA-1) antibody RNA binding protein TIA 1 antibody T-cell-restricted intracellular antigen-1 antibody TIA 1 cytotoxic granule associated RNA binding protein antibody TIA1 cytotoxic granule associated RNA binding protein like 1 antibody TIA1 protein antibody TIAL1 antibody TIAR antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-TIA.112 | |||
|
TIA-112AP | |||
|
TIA.112-FITC | |||
|
PC-TIA | |||
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