General Information

Product

Cornichon Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 90-120 on human Cornichon protein.

Accession #

NCBI: AAC98388.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.51-0.62 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

O95406

Overview

Involved in the selective transport and maturation of TGF-alpha family proteins.

Molecular Function

ER-Golgi transport

Subcellular Location

Endoplasmic reticulum membrane; Golgiapparatus membrane

Expression

Highly expressed in heart, liver, skeletal muscle, pancreas, adrenal medulla and cortex, thyroid, testis, spleen, appendix, peripheral blood lymphocytes and bone marrow.  Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia.

Structure

Belongs to cornichon family, contains transmembrane helix

Alternative Nomenclature

CNI like antibody

CNIH 2 antibody

Cnih3 antibody

Cnil antibody

RGD1304930 antibody

General Information

Product

Golgin A1 Antibody

Description

Affinity Purified Golgin subfamily A member 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 650-700 on mouse Golgin subfamily A member 1 isoform b protein.

Accession #

NCBI:  NP_001277578.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q9CW79

Overview

Probably involved in maintaining Golgi structure. May play a role in acrosome formation and spermatogenesis.

Molecular Function

Protein targeting to Golgi

Subcellular Location

Golgi apparatus > Golgi stack membrane; Peripheral Membrane protein

Expression

Present in the acrosome of spermatids up to the late cap-stage, but not in mature spermatozoa.

Structure

Extended rod-like protein with coiled-coil domains; Contains 1 GRIP domain.

Alternative Nomenclature

Gap junction protein alpha 4 37kD antibody

Golga 1 antibody

Golgi autoantigen golgin subfamily A member 1 antibody

Golgin A1 antibody

Golgin subfamily A member 1 antibody

Golgin-97 antibody

MGC33154 antibody

General Information

Product

Golgin A5 Antibody

Description

Affinity Purified Golgin subfamily A member 5 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 660-710 on human Golgin subfamily A member 5 protein.

Accession #

NCBI:  NP_005104.3

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q8TBA6

Overview

Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.

Molecular Function

Protein homodimerization activity; Rab GTPase binding

Subcellular Location

Golgi apparatus membrane; Single-pass type IV membrane protein

Expression

Ubiquitous. Highly expressed in seminiferous tubules and Leydig cells in testis, and detected at much lower levels in the other tissues tested. Expression is very low or not detectable in spermatozoa.

Structure

Homodimer. Interacts with RAB1A that has been activated by GTP-binding, and possibly also with OCRL1. Interacts with isoform CASP of CUX1.

Alternative Nomenclature

Cell proliferation inducing gene 31 antibody

GOLGA5 antibody

Golgi autoantigen golgin subfamily a 5 antibody

Golgi integral membrane protein 5 antibody

Golgin 84 antibody

Golgin A5 antibody

Golgin subfamily A member 5 antibody

Golgin84 antibody

GOLIM5 antibody

Protein Ret-II antibody

PTC5 antibody

RET fused gene 5 protein antibody

Ret II antibody

RET-fused gene 5 protein antibody

RFG 5 antibody

General Information

Product

Golgin A4 Antibody

Description

Affinity Purified Golgin-245 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 2025-2075 on human Golgin-245 protein.

Accession #

GenBank: AAC51791.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q13439

Overview

May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1.

Molecular Function

GTPase binding; Golgi to plasma membrane protein transport

Subcellular Location

Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Golgi apparatus

Expression

Homodimer. Interacts with GTP bound ARL1. Interacts with MACF1.

Structure

Extended rod-like protein with coiled-coil domains. Ctonains 1 GRIP domain.

Alternative Nomenclature

256 kDa golgin antibody

72.1 protein antibody

GCP2 antibody

GOLG antibody

GOLGA4 antibody

Golgin subfamily A member 4 antibody

golgin-240 antibody

Golgin-245 antibody

MU-RMS-40.18 antibody

p230 antibody

Protein 72.1 antibody

Trans-Golgi p230 antibody

General Information

Product

Golgin A3 Antibody

Description

Affinity Purified Golgin subfamily A member 3 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Rat

Immunogen

Synthetic peptide taken within amino acid region 1400-1450 on human Golgin subfamily A member 3 isoform 1 protein.

Accession #

NCBI:  NP_005886.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q08378

Overview

Golgi auto-antigen; probably involved in maintaining Golgi structure.

Molecular Function

Transporter activity

Subcellular Location

Cytoplasm. Golgi apparatus › Golgi stack membrane; Peripheral membrane protein

Expression

Expressed in all tissues tested. Expressed in liver, testis, lung, heart, salivary gland and kidney.

Structure

Homodimer. Interacts with GOLGA7. Isoform 1 interacts with GOPC while isoform 3 does not.

Alternative Nomenclature

GCP170 antibody

GOLGA 3 antibody

Golgi autoantigen antibody

Golgi complex-associated protein of 170 kD antibody

Golgi peripheral membrane protein antibody

Golgin 160 antibody

Golgin subfamily a 3 antibody

HGNC:4426 antibody

Male enhanced antigen 2 antibody

MEA2 antibody

SY2/SY10 protein antibody

General Information

Product

Golgin A2 Antibody Affinity Purified

Description

Affinity Purified Golgin subfamily A member 2 Antibody

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 925-975 on human Golgin subfamily A member 2 isoform X3 protein.

Accession #

NCBI:  XP_005251989.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

UPI000387D38E

Overview

Golgi auto-antigen; probably involved in maintaining cis-Golgi structure.

Molecular Function

Protein Kinase binding; Syntaxin binding; Mitotic Cell Cycle

Subcellular Location

Golgi apparatus › Golgi stack membrane; Peripheral membrane protein

Structure

Part of a larger oligomeric complex. Interacts with p115 (By similarity). Interacts with RAB1B that has been activated by GTP-binding. Interacts with GORASP1/GRASP65 and ZFPL1.

Alternative Nomenclature

130 kDa cis Golgi matrix protein antibody

Cis golgi matrix protein GM130 antibody

GM130 antibody

GM130 autoantigen antibody

GOLGA 2 antibody

Golgi autoantigen antibody

Golgi autoantigen golgin subfamily a 2 antibody

Golgi matrix protein GM130 antibody

Golgin 95 antibody

golgin A2 antibody

Golgin subfamily A member 2 antibody

Golgin-95 antibody

MGC20672 antibody

SY11 protein antibody

General Information

Product

VPS29 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Chicken, Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 133-183 on rat Vacuolar Protein Sorting-Associated Protein 29.

Accession #

NCBI:  NP_001099402.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-1.50 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9UBQ0

Overview

Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3.

Molecular Function

Metal ion binding, Phosphoserine phosphatase activity

Subcellular Location

Cytoplasm. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Early endosome Curated. Late endosome.

Expression

Ubiquitous. Highly expressed in heart, lung, placenta, spleen, peripheral blood leukocytes, thymus, colon skeletal muscle, kidney and brain.

Structure

Component of the heterotrimeric retromer cargo-selective complex (CSC), also described as vacuolar protein sorting subcomplex (VPS), formed by VPS26 (VPS26A or VPS26B), VPS29 and VPS35 (PubMed:11102511, PubMed:16737443, PubMed:17891154). The CSC has a highly elongated structure with VPS26 and VPS29 binding independently at opposite distal ends of VPS35 as central platform. The CSC is believed to associate with variable sorting nexins to form functionally distinct retromer complex variants.

Alternative Nomenclature

DC15 antibody

DC7 antibody

DKFZp564F0223 antibody

FLJ20492 antibody

hVPS29 antibody

PEP11 antibody

Retromer protein antibody

Vacuolar protein sorting 29 antibody

Vacuolar sorting protein VPS29/PEP11 antibody

Vesicle protein sorting 29 antibody

VPS 29 antibody

x 007 protein antibody

General Information

Product

VPS26 Antibody

Description

Affinity Purified Vacuolar protein sorting-associated protein 26A Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acids 315-375 on human VPS26 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.56 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

O75436

Overview

Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3.

Molecular Function

protein transporter activity

Subcellular Location

cytoplasm, endosome membrane, preipheral membrane protein (Note: Localizes to tubular profiles adjacent to endosomes. Predominantly found in early not late endosomes)

Expression

Down-regulated in Alzheimer disease. No polymorphism or variant is however associated with Alzheimer disease for VPS26A.

Alternative Nomenclature

FLJ12930 antibody

FLJ12930 antibody

HB 58 antibody

Hbeta 58 antibody

Hbeta 58 homolog antibody

MGC94168 antibody

PEP 8A antibody

Vacuolar protein sorting 26 A antibody

Vacuolar protein sorting 26 homolog A yeast antibody

Vacuolar protein sorting associated protein 26A antibody

Vesicle protein sorting 26A antibody

VPS 26 antibody

VPS 26A antibody

General Information

Product

PGAP3 Antibody

Description

Affinity Purified Post-GPI attachment to proteins 3 Antibody N-epitope

Verified Applications

DB, ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human PGAP3 protein.

Accession #

GenBank:  BC010652

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:50,000

ELISA

1:50,000

Immunoprecipitation

1:150

Western Blot

1:500-1:1,000

Protein

Uniprot #

Q96FM1

Overview

Involved in lipid remodeling steps of GPI-anchor maturation.  Remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchor proteins.

Molecular Function

Hydrolase activity, acting on ester bonds, GPI-anchor biosynthesis

Subcellular Location

Golgi apparatus; Endoplasmic reticulum; Membrane

Expression

Ubiqutously expressed; highest levels in thyroid in placenta

Structure

Belongs to PGAP3 family

Alternative Nomenclature

AGLA546 antibody

CAB2 antibody

Gene coamplified with ERBB2 protein antibody

hCOS16 antibody

MGC9753 antibody

PER1 antibody

Per1 like domain containing 1 antibody

PERLD1 antibody

Post GPI attachment to proteins 3 antibody

PP1498 antibody

General Information

Product

PGAP3 Antibody

Description

Affinity Purified Post-GPI attachment to proteins 3 Antibody Mid-Region

Verified Applications

DB, ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 10-60 on human PGAP3 protein.

Accession #

GenBank:  BC010652

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Mid-Region

Storage

-20⁰C for long term storage

Application Protocol

DB

1:50,000

ELISA

1:50,000

Immunoprecipitation

1:150

Western Blot

1:500-1:1,000

Protein

Uniprot #

Q96FM1

Overview

Involved in lipid remodeling steps of GPI-anchor maturation.  Remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchor proteins.

Molecular Function

Hydrolase activity, acting on ester bonds, GPI-anchor biosynthesis

Subcellular Location

Golgi apparatus; Endoplasmic reticulum; Membrane

Expression

Ubiqutously expressed; highest levels in thyroid in placenta

Structure

Belongs to PGAP3 family

Alternative Nomenclature

AGLA546 antibody

CAB2 antibody

Gene coamplified with ERBB2 protein antibody

hCOS16 antibody

MGC9753 antibody

PER1 antibody

Per1 like domain containing 1 antibody

PERLD1 antibody

Post GPI attachment to proteins 3 antibody

PP1498 antibody