General Information

Product

IFI16 Antibody Affinity Purified

Description

Affinity Purified Gamma-interferon-inducible protein 16 isoform 1 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 140-190 on human IFI16 protein

Accession #

NCBI:  NP_001193496.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.58-0.62 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q16666

Overview

Binds double-stranded DNA. Binds preferentially to supercoiled DNA and cruciform DNA structures. Seems to be involved in transcriptional regulation. May function as a transcriptional repressor. Could have a role in the regulation of hematopoietic differentiation through activation of unknown target genes. Controls cellular proliferation by modulating the functions of cell cycle regulatory factors including p53/TP53 and the retinoblastoma protein.

Molecular Function

Core promoter binding, identical protein binding, transcription factor binding, double-standard DNA binding, poly(A) RNA binding

Subcellular Location

Nucleus, cytoplasm (Note: Cellular distribution is dependent on acetylation status of multipartite nuclear localization signal(NLS); NLS acetylation promotes cytoplasmic localization. Localizes in nucleus during human herbes simplex virus 1 infection)

Expression

Expressed in peripheral blood leukocytes, fibroblasts and lymphoid cells. Present in myeloid precursors (CD34+) and throughout monocyte development, but its expression is down-regulated in erythroid and polymorphonuclear precursor cells. Present in prosta

Alternative Nomenclature

IFI16 antibody

Gamma interferon inducible protein 16 antibody

Ifi204 antibody

IFNGIP1 antibody

interferon activated gene 204 antibody

Interferon gamma inducible protein 16 antibody

p204 antibody

PYHIN2 antibody

General Information

Product

ILK Antibody

Description

Affinity Purified Integrin-linked protein kinase Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 400-452 on human Integrin-linked protein kinase.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.66-0.87 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q13418

Overview

Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway.

Molecular Function

ATP binding, protein kinase binding, protein serine/threonine kinase activity, signal transducer activity

Subcellular Location

Cell junction, cell membrane, peripheral membrane protein, cytoplasmic side, cell projection

Expression

Highly expressed in heart followed by skeletal muscle, pancreas and kidney. Weakly expressed in placenta, lung and liver.

Alternative Nomenclature

59 kDa serine/threonine protein kinase antibody

DKFZp686F1765 antibody

ILK 1 antibody

ILK 2 antibody

ILK antibody

Integrin linked kinase 2 antibody

Integrin-linked protein kinase antibody

p59 antibody

p59ILK antibody

General Information

Product

Junctional Adhesion Molecule 1 Antibody

Description

Affinity Purified Junctional adhesion molecule A Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Monkey, Mouse, Panda, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-299 on human Junctional Adhesion Molecule A protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.52-0.63 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9Y624

Overview

Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3.  Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

Subcellular Location

Cell junction, cell membrane, single-pass type I membrane protein (Note: Localized at tight junctions of both epithelial and endothelial cells)

Alternative Nomenclature

9130004G24 antibody

AA638916 antibody

CD 321 antibody

ESTM33 antibody

F11 receptor antibody

F11R antibody

JAM 1 antibody

JAM A antibody

JCAM antibody

Junction adhesion molecule 1 antibody

KAT antibody

Ly106 antibody

PAM1 antibody

Platelet adhesion molecule 1 antibody

Platelet F11 receptor antibody

PRO301 antibody

UNQ264/PRO301 antibody

General Information

Product

LAMP1 Antibody

Description

Affinity Purified Lysosome-associated membrane glycoprotein 1 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 300-350 on human LAMP1 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P11279

Overview

Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.

Molecular Function

Enzyme binding

Subcellular Location

Cell membrane, single-pass type I membrane protein, endosome membrane, lysosome membrane (Note:This protein shuttles between lysosomes, endosomes, and plasma membrane. Colocalizes with OSBPL1A at the late endosome)

Alternative Nomenclature

CD107 antigen like family member A antibody

LAMP 1 antibody

LAMPA antibody

LGP120 antibody

lgpA antibody

Lysosomal Associated Membrane Protein 1 antibody

General Information

Product

Lysozyme Antibody

Description

Affinity Purified Homo sapiens lysozyme gene Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Partially purified full-length lysozyme protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.57 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P61626

Overview

Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

Molecular Function

Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase

Subcellular Location

Secreted

Structure

Monomer

Alternative Nomenclature

4 beta N acetylmuarmidase C antibody

1 antibody

4-beta-N-acetylmuramidase C antibody

EC 3.2.1.17 antibody

LYSC_HUMAN antibody

Lysosyme antibody

Lysozyme (renal amyloidosis) antibody

Lysozyme C antibody

LYZ antibody

LZM antibody

Renal amyloidosis antibody

General Information

Product

MUC1 Antibody

Description

Affinity Purified Mucin 1, transmembrane Antibody

Verified Applications

ELISA, IHC, IP

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on MUCIN1 protein.

Accession #

NCBI:  NM_182741.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Western Blot

1:500

Protein

Uniprot #

P15941

Overview

The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.

Molecular Function

transcription cofactor activity

Subcellular Location

Cell membrane, Cytoplasm, Membrane, Nucleus, Secreted

Expression

Expressed on the apical surface of epithelial cells, especially of airway passages, breast and uterus. Also expressed in activated and unactivated T-cells. Overexpressed in epithelial tumors, such as breast or ovarian cancer and also in non-epithelial tumor cells. Isoform 7 is expressed in tumor cells only.

Alternative Nomenclature

ADMCKD antibody

Breast carcinoma-associated antigen DF3 antibody

CA 15 3 antibody

CD227 antigen antibody

DF3 antigen antibody

EMA antibody

Episialin antibody

Epithelial basement membrane antigen antibody

H23 antigen antibody

KL 6 antibody

MAM 6 antibody

MCD antibody

MCKD1 antibody

MUC 1 antibody

Peanut-reactive urinary mucin antibody

Polymorphic epithelial mucin antibody

Tumor associated epithelial membrane antigen antibody

General Information

Product

NKG2D Antibody Affinity Purified

Description

Affinity Purified NKG2-D type II integral membrane protein Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Monkey, Panda

Immunogen

Synthetic peptide taken within amino acid region 180-230 on rat NKG2D protein.

Accession #

NCBI:  NP_598196.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

O70215

Overview

Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells

Molecular Function

MHC class Ib receptor activity

Subcellular Location

Cell membrane, Membrane

Expression

Expressed by natural killer cells and by resting thoracic duct CD4+ and CD8+ T-cells, but not by thymocytes or other hemopoietic cells. Expressed by DC cells

Alternative Nomenclature

CD314 antibody

D12S2489E antibody

Killer cell lectin like receptor subfamily K member 1 antibody

KLR antibody

NK cell receptor D antibody

NK lectin-like receptor antibody

NKG2 D activating NK receptor antibody

NKLLR antibody

NKR P2 antibody

General Information

Product

PALB2 Antibody

Description

Affinity Purified Partner and localizer of BRCA2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1,130-1,186 on human PALB2 protein.

Accession #

GenBank: AAH44254.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q86YC2

Molecular Function

DNA binding

Subcellular Location

Nucleus

Structure

Homooliomer; dissociated once DNA damage has occurred which allows association with BRCA1.

Alternative Nomenclature

4732427B05 antibody

BC066140 antibody

DKFZp667I166 antibody

DKFZp686E1054 antibody

FANCN antibody

FLJ21816 antibody

OTTMUSP00000025884 antibody

PALB2 antibody

Partner and localizer of BRCA2 antibody

PNCA3 antibody

RGD1304759 antibody

General Information

Product

PAX1 Antibody

Description

Affinity Purified Paired Box Protein 

Pax-1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Rat

Immunogen

Synthetic peptide corresponding to unique sequence within amino acid region 210-260 on human PAX1 protein.

Accession #

NCBI: NP_006183.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75-0.95 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P15863

Overview

A transcriptional activator that may serve a function in the formation of segmented structures of the embryo.  Also may serve an important function in the normal development of the vertebral column.

Molecular Function

DNA binding, Activator, Developmental protein

Subcellular Location

Nucleus

Alternative Nomenclature

HUP48 antibody

OTTHUMP00000030407 antibody

Paired box 1 antibody

Paired domain gene HuP48 antibody

PAX 1 antibody

General Information

Product

PAX3 Antibody

Description

Affinity Purified Paired Box Protein Pax-3 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on PAX3 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

.64-.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P23760

Overview

Is a transcription factor that may regulate cell proliferation, migration and apoptosis.  Plays a role in neural development and myogenesis.

Molecular Function

Developmental protein, chromatin binding, sequence-specific DNA binding

Subcellular Location

Nucleus

Structure

Capable of binding to DNA as a homodimer or a heterodimer with PAX7.  Interacts with DAXX and TBX18.

Alternative Nomenclature

CDHS antibody

HUP 2 antibody

MGC120381 antibody

MGC120382 antibody

MGC120383 antibody

MGC120384 antibody

MGC134778 antibody

Paired box 3 antibody

paired box homeotic gene 3 antibody

paired domain gene 3 antibody

PAX 3 antibody

PAX3/FKHR fusion gene antibody

Waardenburg syndrome 1 antibody

WS 1 antibody

WS3 antibody