General Information

Product

Zika Virus P2K Antibody

Description

Affinity Purified Zika Virus Protein 2K Antibody

Verified Applications

ELISA

Host

Rabbit

Species Cross Reactivity

Zika Virus

Immunogen

23 mer Synthetic peptide taken from aa 2247 through 2269 of the ZIKA polyprotein AHL43505.

Accession #

NCBI:  AHL43505

Uniprot:  UPI000764CF24

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

General Information

Product

Zika Virus NS3 Antibody

Description

Affinity Purified Zika Virus Nonstructural protein NS3 Antibody

Verified Applications

ELISA

Host

Rabbit

Species Cross Reactivity

Zika Virus

Immunogen

Synthetic peptide taken within amino acid region 1-50 on Zika virus non structural protein NS3.

Accession #

NCBI:  YP_009227202

Uniprot:  UPI000764CEE5

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

General Information

Product

Zika Virus NS2 Antibody

Description

Affinity Purified Zika Virus Nonstructural protein NS2 Antibody

Verified Applications

ELISA

Host

Rabbit

Species Cross Reactivity

Zika Virus

Immunogen

Synthetic peptide taken within amino acid region 1300-1350 on Zika virus non structural protein NS2.

Accession #

GenBank: AHL43505

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

W8Q6T7

Overview

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

Molecular Function

Helicase, Hydrolase, Nucleotidyltransferase, Protease, RNA-directed RNA polymerase, Serine protease, Transferase

Subcellular Location

Virion membrane, Multi-pass membrane protein

Alternative Nomenclature

NS2 zika virus antibody
RNA-dependent RNA polymerase NS2 antibody
nonstructural protein 2 antibody

General Information

Product

Zika Virus NS1 Antibody

Description

Affinity Purified Zika Virus Nonstructural protein NS1 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Zika Virus

Immunogen

Synthetic peptide taken within amino acid region 100-200 on Zika virus non structural protein NS1.

Accession #

NCBI:  YP_009227199.1

Uniprot:  UPI000764CEEF

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:250 - 1:500

General Information

Product

Syncytin A Antibody

Description

Affinity Purified Envelope glycoprotein syncytin-A Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 180-230 on rat Envelope glycoprotein syncytin-A protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q5G5D4

Overview

This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5 (PubMed:10708449, PubMed:12050356, PubMed:23492904).3 Publications

Endogenous envelope proteins may have kept, lost or modified their original function during evolution.

Molecular Function

Anatomical structure morphogenesis, syncytium formation

Subcellular Location

Cell membrane

Expression

Expressed at higher level in placental syncytiotrophoblast. Expressed at intermediate level in testis. Seems also to be found at low level in adrenal tissue, bone marrow, breast, colon, kidney, ovary, prostate, skin, spleen, thymus, thyroid, brain and trachea. Both mRNA and protein levels are significantly increased in the brain of individuals with multiple sclerosis, particularly in astrocytes and microglia.

Structure

The cytoplasmic region is essential for the fusiogenic function.

The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequence inhibit immune function in vitro and in vivo.

Alternative Nomenclature

Endogenous retrovirus group W member 1 antibody
env antibody
Env-W antibody
Envelope polyprotein gPr73 antibody
Enverin antibody
ERVW antibody
ERVW-1 antibody
Gp24 antibody
Gp50 antibody
HERV-7q Envelope protein antibody
HERV-W envelope protein antibody
HERVW antibody
SU antibody
Syncytin A antibody
TM antibody
Transmembrane protein antibody

General Information

Product

ERVW-1 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 480-538 on human ERVW-1 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9UQF0

Overview

This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5 (PubMed:10708449, PubMed:12050356, PubMed:23492904).3 Publications

Endogenous envelope proteins may have kept, lost or modified their original function during evolution.

Molecular Function

Anatomical structure morphogenesis, syncytium formation

Subcellular Location

Cell membrane

Expression

Expressed at higher level in placental syncytiotrophoblast. Expressed at intermediate level in testis. Seems also to be found at low level in adrenal tissue, bone marrow, breast, colon, kidney, ovary, prostate, skin, spleen, thymus, thyroid, brain and trachea. Both mRNA and protein levels are significantly increased in the brain of individuals with multiple sclerosis, particularly in astrocytes and microglia.

Structure

The cytoplasmic region is essential for the fusiogenic function.

The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequence inhibit immune function in vitro and in vivo.

Alternative Nomenclature

Endogenous retrovirus group W member 1 antibody
env antibody
Env-W antibody
Envelope polyprotein gPr73 antibody
Enverin antibody
ERVW antibody
ERVW-1 antibody
Gp24 antibody
Gp50 antibody
HERV-7q Envelope protein antibody
HERV-W envelope protein antibody
HERVW antibody
SU antibody
Syncytin 1 antibody
TM antibody
Transmembrane protein antibody

General Information

Product

Syncytin 2 Antibody

Description

Affinity Purified Envelope glycoprotein syncytin-B Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 380-430 on human Envelope glycoprotein syncytin-B protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q8BI41

Overview

This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process (PubMed:18988732).1 Publication

Endogenous envelope proteins may have kept, lost or modified their original function during evolution but this one can still make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein mediates receptor recognition, while the transmembrane protein anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (PubMed:14694139).

Molecular Function

Syncytium formation

Subcellular Location

Virion, Cell membrane

Expression

Expressed at higher level in placenta. Expressed at lower level in adrenal, bone marrow, brain, breast, colon, kidney, lung, ovary, peripheral blood lymphocytes, prostate, skin, spleen, testis, thymus, thyroid, trachea.

Structure

Contains the CKS-17 immunosuppressive domain present in many retroviral envelope proteins. As a synthetic peptide, it inhibits immune function in vitro and in vivo.

Alternative Nomenclature

Endogenous retrovirus group FRD member 1 antibody
Envelope polyprotein antibody
ERVFRD-1 antibody
HERV FRD 6p24.1 provirus ancestral Env polyprotein antibody
HERV FRD antibody
HERV FRD provirus ancestral Env polyprotein antibody
SU antibody
Syncytin 2 antibody
Syncytin B antibody
TM antibody
Transmembrane protein antibody
UNQ6191 antibody

General Information

Product

Syncytin 2 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 80-130 on human Syncytin-2 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P60508

Overview

This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process (PubMed:18988732).1 Publication

Endogenous envelope proteins may have kept, lost or modified their original function during evolution but this one can still make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein mediates receptor recognition, while the transmembrane protein anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (PubMed:14694139).

Molecular Function

Syncytium formation

Subcellular Location

Virion, Cell membrane

Expression

Expressed at higher level in placenta. Expressed at lower level in adrenal, bone marrow, brain, breast, colon, kidney, lung, ovary, peripheral blood lymphocytes, prostate, skin, spleen, testis, thymus, thyroid, trachea.

Structure

Contains the CKS-17 immunosuppressive domain present in many retroviral envelope proteins. As a synthetic peptide, it inhibits immune function in vitro and in vivo.

Alternative Nomenclature

Endogenous retrovirus group FRD member 1 antibody
Envelope polyprotein antibody
ERVFRD-1 antibody
HERV FRD 6p24.1 provirus ancestral Env polyprotein antibody
HERV FRD antibody
HERV FRD provirus ancestral Env polyprotein antibody
SU antibody
Syncytin 2 antibody
Syncytin B antibody
TM antibody
Transmembrane protein antibody
UNQ6191 antibody

General Information

Product

SARS-CoV-2 SPIKE surface glycoprotein Antibody

Description

Affinity Purified surface glycoprotein [Severe acute respiratory syndrome coronavirus 2] Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Virus

Immunogen

Synthetic peptide taken from unique amino acid sequence on surface glycoprotein [Severe acute respiratory syndrome coronavirus 2].

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Alternative Nomenclature

Surface Glycoprotein

Severe acute respiratory syndrome Coronavirus 2

WUHAN-S

General Information

Product

SARS-CoV-2 ORF7a Antibody

Description

Affinity Purified ORF7a protein [Severe acute respiratory syndrome coronavirus 2] Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Virus

Immunogen

Synthetic peptide taken from unique amino acid sequence on ORF7a [Severe acute respiratory syndrome coronavirus 2].

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Alternative Nomenclature

ORF7A Protein

Severe acute respiratory syndrome Coronavirus 2

WUHAN-ORF7A