General Information

Product

trp Antibody Affinity Purified

Description

Affinity Purified Transient Receptor Potential isoform A Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Drosophila melanogaster

Immunogen

Synthetic peptide corresponding to unique amino acid sequences on D. melanogaster Transient Receptor Potential isoform A protein.

Accession #

NCBI:  NP_476768.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.62 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:10,000

Protein

Uniprot #

P19334

Overview

A light-sensitive calcium channel that is required for inositide-mediated Ca2+ entry in the retina during phospholipase C (PLC)-mediated phototransduction. Ca2+ influx may then feed back and inhibit PLC, thereby facilitating phosphatidylinositol 4,5 bisphosphate (PIP2) recycling.

Molecular Function

Calcium channel, Ion channel, Calmodulin activity

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Expressed predominantly in the rhabdomeres of photoreceptor cells. Expressed in the third antennal segment and in the olfactory segment at approximately 70 hours after puparium formation during antennal development.

Structure

The C-terminus interacts with a PDZ domain of inaD to form the core of the inaD signaling complex. Other members of the complex include norpA (PLC), inaC (PKC), and possibly trpl, ninaC, FKBP59, calmodulin and rhodopsin. Forms homomultimers and heteromult

Alternative Nomenclature

DmTRP antibody

dTRP antibody

Transient receptor potential antibody

General Information

Product

Calretinin Antibody

Verified Applications

CM, DB, ELISA, IF, IHC-P, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within amino acid region 220-271. Conjugated to Keyhole Limpet Haemocyanin (KLH). Peptide was covalently modified.

Sequence:

L DALLKDLYEK NKKEMNIQQL TNYRKSVMSL AEGKLYRKD LEIVLCSEPP M

Accession #

GenBank: CAA39991.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:50-1:200

Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Immunoprecipitation

1:200

Western Blot

1:500. Predicted molecular weight: 32 kDa

Protein

Uniprot #

P22676

Overview

Calcium binding protein which is abundant in auditory neurons.

Molecular Function

Calcium ion binding; Metal binding

Subcellular Location

Cytoplasm; gap junction; nucleus

Expression

Brain

Structure

Belongs to calbindin family.  Has 6 EF-hand domains.

Alternative Nomenclature

29 kDa calbindin antibody

CAB29 antibody

CAL2 antibody

CALB2 antibody

Calbindin 2 29kDa antibody

Calbindin 2 antibody

Calbindin D29K antibody

Calbindin2 antibody

Calretinin antibody

CR antibody

General Information

Product

Calretinin Antibody

Description

Affinity Purified Calretinin Antibody N-epitope

Verified Applications

CM, DB, ELISA, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human Calretinin protein.

Accession #

GenBank: CAA39991.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:50-1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:50-1:200

Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P22676

Overview

Calcium binding protein which is abundant in auditory neurons.

Molecular Function

Calcium ion binding; Metal binding

Subcellular Location

Cytoplasm; gap junction; nucleus

Expression

Brain

Structure

Belongs to calbindin family.  Has 6 EF-hand domains.

Alternative Nomenclature

29 kDa calbindin antibody

CAB29 antibody

CAL2 antibody

CALB2 antibody

Calbindin 2 29kDa antibody

Calbindin 2 antibody

Calbindin D29K antibody

Calbindin2 antibody

Calretinin antibody

CR antibody

General Information

Product

E-Cadherin Antibody

Description

Affinity Purified E-cadherin 1 Antibody N-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 50-100 on human E-cadherin 1 protein.

Accession #

GenBank: ADC53120.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

D3XNU5

Overview

Cadherins are calcium dependent cell adhesion proteins.

Molecular Function

Calcium ion binding;

Subcellular Location

Membrane; Single-pass type I  membrane protein

Structure

Repeat; Transmembrane helix

Alternative Nomenclature

Arc 1 antibody

Cadherin 1 antibody
cadherin 1 type 1 E-cadherin antibody
Cadherin1 antibody
CAM 120/80 antibody
CD324 antigen antibody
CDH1 antibody
CDHE antibody
E-Cad/CTF3 antibody
E-cadherin antibody
Epithelial cadherin antibody
epithelial calcium dependant adhesion protein antibody
LCAM antibody
Liver cell adhesion molecule antibody
UVO antibody
Uvomorulin antibody

General Information

Product

E-Cadherin Antibody

Description

Affinity Purified E-cadherin 1 Antibody Mid-Region

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 350-400 human E-cadherin 1 protein.

Accession #

GenBank: ADC53120.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Mid-Region

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

D3XNU5

Overview

Cadherins are calcium dependent cell adhesion proteins.

Molecular Function

Calcium ion binding;

Subcellular Location

Membrane; Single-pass type I  membrane protein

Structure

Repeat; Transmembrane helix

Alternative Nomenclature

Arc 1 antibody

Cadherin 1 antibody
cadherin 1 type 1 E-cadherin antibody
Cadherin1 antibody
CAM 120/80 antibody
CD324 antigen antibody
CDH1 antibody
CDHE antibody
E-Cad/CTF3 antibody
E-cadherin antibody
Epithelial cadherin antibody
epithelial calcium dependant adhesion protein antibody
LCAM antibody
Liver cell adhesion molecule antibody
UVO antibody
Uvomorulin antibody

General Information

Product

E-Cadherin Antibody C-epitope

Description

Affinity Purified E-cadherin 1 Antibody

C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region  650-700 on human E-cadherin 1 protein.

Accession #

GenBank: ADC53120.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

D3XNU5

Overview

Cadherins are calcium dependent cell adhesion proteins.

Molecular Function

Calcium ion binding;

Subcellular Location

Membrane; Single-pass type I  membrane protein

Structure

Repeat; Transmembrane helix

Alternative Nomenclature

Arc 1 antibody

Cadherin 1 antibody
cadherin 1 type 1 E-cadherin antibody
Cadherin1 antibody
CAM 120/80 antibody
CD324 antigen antibody
CDH1 antibody
CDHE antibody
E-Cad/CTF3 antibody
E-cadherin antibody
Epithelial cadherin antibody
epithelial calcium dependant adhesion protein antibody
LCAM antibody
Liver cell adhesion molecule antibody
UVO antibody
Uvomorulin antibody

General Information

Product

CAMKII gamma Antibody

Description

Affinity Purified Calcium/calmodulin-dependent protein kinase type II subunit gamma Antibody

Verified Applications

CM, DB, ELISA, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse

Immunogen

Synthetic peptide taken within amino acid region 400-455 on human CAMKII gamma protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.8 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q13555

Overview

Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.

Molecular Function

Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase

Subcellular Location

Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side

Expression

Skeletal muscle

Structure

CAMK2 is composed of 4 different chains: alpha (CAMK2A), beta (CAMK2B), gamma (CAMK2G), and delta (CAMK2D). The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 12 subunits with two hexameric rings stacked one on top of the other.

Alternative Nomenclature

Calcium/calmodulin dependent protein kinase type 1G antibody

CaM kinase I gamma antibody

CaM kinase IG antibody

CaMK-like CREB kinase III antibody

Camk1g antibody

CLICK III antibody

VWS1 antibody

General Information

Product

CAMKII gamma Antibody

Description

Affinity Purified Calcium/calmodulin-dependent protein kinase type II subunit gamma isoform 3 Antibody N-epitope

Verified Applications

CM, DB, ELISA, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 350-400 on human CAMKII gamma protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.8 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q13555

Overview

Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.

Molecular Function

Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase

Subcellular Location

Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side

Expression

Skeletal muscle

Structure

CAMK2 is composed of 4 different chains: alpha (CAMK2A), beta (CAMK2B), gamma (CAMK2G), and delta (CAMK2D). The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 12 subunits with two hexameric rings stacked one on top of t

Alternative Nomenclature

Calcium/calmodulin dependent protein kinase type 1G antibody

CaM kinase I gamma antibody

CaM kinase IG antibody

CaMK-like CREB kinase III antibody

Camk1g antibody

CLICK III antibody

VWS1 antibody

General Information

Product

TGM1 Antibody

Description

Affinity Purified Coagulation factor XIII A chain Antibody C-epitope

Verified Applications

CM, ELISA, ICC, IHC, IF, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on Coagulation factor XIIIA chain precursor

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61-0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

Dot Blot

1:30,000

ELISA

1:30,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Western Blot

1:450

Protein

Uniprot #

Q8BH61

Overview

Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.

Molecular Function

metal ion binding, protein-glutamine gamma-glutamyltransferase activity

Subcellular Location

Cytoplasm, Secreted

Structure

Tetramer of two A chains and two B chains

Alternative Nomenclature

ARCI1 antibody

Epidermal TGase antibody

ICR2 antibody

KTG antibody

LI antibody

LI1 antibody

Protein glutamine gamma glutamyltransferase K antibody

TG(K) antibody

TGase 1 antibody

TGASE antibody

TGase K antibody

TGK antibody

TGM1 antibody

Transglutaminase 1 (K polypeptide epidermal type I, protein glutamine gamma glutamyltransferase) antibody

Transglutaminase 1 antibody

Transglutaminase K antibody

General Information

Product

TGM1 Antibody Affinity Purified

Description

Affinity Purified Coagulation factor XIII A chain Antibody N-epitope

Verified Applications

CM, ELISA, ICC, IHC, IF, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on Coagulation factor XIIIA chain precursor

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61-0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

DB

1:30,000

ELISA

1:30,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Western Blot

1:450

Protein

Uniprot #

Q8BH61

Overview

Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin (By similarity).

Molecular Function

metal ion binding, protein-glutamine gamma-glutamyltransferase activity

Subcellular Location

Cytoplasm, Secreted

Structure

Tetramer of two A chains and two B chains

Alternative Nomenclature

ARCI1 antibody

Epidermal TGase antibody

ICR2 antibody

KTG antibody

LI antibody

LI1 antibody

Protein glutamine gamma glutamyltransferase K antibody

TG(K) antibody

TGase 1 antibody

TGASE antibody

TGase K antibody

TGK antibody

TGM1 antibody

Transglutaminase 1 (K polypeptide epidermal type I, protein glutamine gamma glutamyltransferase) antibody

Transglutaminase 1 antibody

Transglutaminase K antibody