General Information

Product

GPCR GPR40 Antibody

Description

Affinity Purified FFAR1 protein Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 150-200 on human FFA1 protein.

Accession #

GenBank: AAI20944.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.58-0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q0IJ71

Molecular Function

G-protein coupled receptor activity

Subcellular Location

Integral component of membrane

Alternative Nomenclature

FFA1R antibody

Free fatty acid receptor 1 antibody

G protein coupled receptor 40 antibody

GPR40 antibody

General Information

Product

FFAR3 Antibody

Description

Affinity Purified Free fatty acid receptor A3 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 270-320  on human FFAR3 protein.

Accession #

NCBI:  NP_005295.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.58-0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

O14843

Overview

G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins. Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation (PubMed:12711604). 

Molecular Function

G-protein coupled receptor activity; Lipid binding

Subcellular Location

Cell Membrane; Multi-Pass Membrane Protein

Expression

Highest level in adipose tissue, and lower expression across all tissues tested. Expressed in sympathetic ganglia.

Structure

Belongs to the G-protein coupled receptor 1 family.

Alternative Nomenclature

FFA3R antibody

Free fatty acid receptor 3 antibody

G protein coupled receptor 41 antibody

GPCR41 antibody

GPR41 antibody

gpr42 antibody

General Information

Product

Glucose transporter GLUT4 Antibody

Description

Affinity Purified Solute carrier family 2 , facilitated glucose transporter member 4 Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 450-509 on mouse Solute carrier family 2, facilitated glucose transporter member 4 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DOT Blot

1:4,000

ELISA

1:4,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:1,000

Protein

Uniprot #

P14142

Overview

Insulin-regulated facilitative glucose transporter

Molecular Function

glucose transmembrane transporter activity;insulin-responsive hydrogen:glucose symporter activity

Subcellular Location

Cell membrane, Cytoplasm, Membrane

Expression

Skeletal and cardiac muscles; brown and white fat.

Structure

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily

Alternative Nomenclature

insulin-responsive antibody

Glucose transporter GLUT 4 antibody

GLUT 4 antibody

kug antibody

SLC 2A4 antibody

Solute carrier family 2, facilitated glucose transporter member 4 antibody

General Information

Product

GAPDH Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 75-150 on mouse Glyceraldehyde-3-phosphate dehydrogenase protein.

Accession #

NCBI:  NP_032110.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P16858

Overview

Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively.

Molecular Function

Oxidoreductase, Transferase

Subcellular Location

Cytoplasm, Cytoskeleton, Nucleus

Expression

brain; cerebullum; heart; kidney; liver; skeletal muscle

Structure

Homotetramer

Alternative Nomenclature

AI747587 antibody

cytoplasmic antibody

EC 1.1.1.8 antibody

FLJ26652 antibody

G3PD antibody

Gdc1 antibody

Gdp1 antibody

Glycerol 3 phosphate dehydrogenase 1 antibody

Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic antibody

GPDH antibody

GPDH-C antibody

HTGTI antibody

MGC93453 antibody

MGPD antibody

mKIAA4010 antibody

General Information

Product

Isocitrate dehydrogenase Antibody

Description

Affinity Purified IDH1 Antibody

Verified Applications

CM, ELISA, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 350-414 on human Isocitrate dehydrogenase.

Accession #

GenBank: CAG38738.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61-0.63 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:100

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q6FI37

Overview

Catalytic activity: Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.  Binds 1 magnesium or manganese ion per subunit as cofactor.

Molecular Function

Magnesium; Manganese; Metal-binding; NADP

Subcellular Location

Cytoplasm; Peroxisome

Structure

Belongs to icocitrate and isopropylmalate dehydorgenases family

Alternative Nomenclature

Cytosolic NADP isocitrate dehydrogenase antibody

Epididymis luminal protein 216 antibody

Epididymis secretory protein Li 26 antibody

HEL-216 antibody

ICDH antibody

IDCD antibody

IDH antibody

Idh1 antibody

IDP antibody

IDPC antibody

Isocitrate dehydrogenase [NADP] cytoplasmic antibody

NADP dependent isocitrate dehydrogenase cytosolic antibody

NADP(+)-specific ICDH antibody

Oxalosuccinate decarboxylase antibody

PICD antibody

General Information

Product

PCSK9 Antibody

Description

Affinity Purified Proprotein convertase subtilisin/kexin type 9 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 30-60 on the NARC1 protein.

Accession #

NCBI:  NP_705793.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.85-1.25 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

Q80W65

Overview

Crucial player in the regulation of plasma cholesterol homeostasis

Molecular Function

Hydrolase, Protease, Serine protease

Subcellular Location

Cytoplasm, Endoplasmic reticulum, Endosome, Golgi apparatus, Lysosome, Secreted

Expression

Hepatocytes, kidney mesenchymal cells, intestinal ileum, colon epithelia and embryonic brain telencephalon neurons.

Structure

Monomer. Can self-associate to form dimers and higher multimers,Belongs to the peptidase S8 family

Alternative Nomenclature

Convertase subtilisin/kexin type 9 preproprotein antibody

FH3 antibody

HCHOLA3 antibody

LDLCQ1 antibody

NARC 1 antibody

PC 9 antibody

PCSK9 antibody

PSEC0052 antibody

General Information

Product

Niemann Pick C1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1228-1278 on human Niemann-Pick C1 protein.

Accession #

NCBI:  NP_000262.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:4,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

O15118

Overview

Intracellular cholesterol transporter plays an important role in the egress of cholesterol from the endosomal/lysosomal compartment.

Molecular Function

Receptor activity

Subcellular Location

Endosome, Lysosome, Membrane

Expression

Adrenal gland; Cerebral cortex; lung; placenta; lymph node

Structure

Belongs to the patched family.

Alternative Nomenclature

Niemann Pick C1 antibody

Niemann Pick C1 protein precursor antibody

Niemann Pick disease, type C1 antibody

NPC antibody

NPC1 antibody

General Information

Product

NPY2R Antibody

Description

Affinity Purified Neuropeptide Y receptor Y2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 300-381 on human NPY2R protein.

Accession #

GenBank: AAO92062.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DOT Blot

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P49146

Overview

Receptor for neuropeptide Y and peptide YY

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane, Membrane

Expression

High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.

Structure

Belongs to the G-protein coupled receptor 1 family

Alternative Nomenclature

Neuropeptide Y Receptor Type 2 antibody

NPY2R antibody

NPYY2 Receptor antibody

Y2 receptor antibody

General Information

Product

KAT13C / NCOA2 Antibody Affinity Purified

Description

Affinity Purified Nuclear receptor coactivator 2 isoform b Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid 1375-1425 on rat NuCR2/GRIP-1/SRC-2 protein.

Accession #

NCBI:  NP_001071163.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.70-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Alternative Nomenclature

bHLHe75 antibody

Class E basic helix-loop-helix protein 75 antibody

glucocorticoid receptor interacting protein 1 antibody

GRIP 1 antibody

hTIF2 antibody

MED1 antibody

MGC138808 antibody

NCoA 2 antibody

Oncogene FGR antibody

p160 antibody

SRC 2 antibody

TIF2 antibody

General Information

Product

PDE3B Antibody

Description

Affinity Purified cGMP-inhibited 3',5'-cyclic phosphodiesterase B Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Chicken, Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1060-1110 on human PDE3B protein.

Accession #

GenBank:  BAA09306

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.70 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

Dot Blot

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q13370

Overview

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Regulates cAMP binding of RAPGEF3.

Molecular Function

Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding

Subcellular Location

Membrane; Multipass membrane protein

Expression

Abundant in adipose tissues.

Structure

Interacts with PIK3CG. Interacts with RAPGEF3 and PIK3R6.

Alternative Nomenclature

5''-cyclic phosphodiesterase B antibody

adipocyte cAMP phosphodiesterase cGMP inhibited antibody

AI847709 antibody

cAMP Phosphodiesterase, adipocyte, cGMP-inhibited antibody

CGIP1 antibody

CGIPDE B antibody

cGMP inhibited 3 5 cyclic phosphodiesterase B antibody

CGMP inhibited cAMP phophodiesterase antibody

cGMP-inhibited 3'' antibody

Cyclic GMP-inhibited phosphodiesterase B antibody

Cyclic nucleotide phosphodiesterase antibody

HcGIP1 antibody

Phosphodiesterase 3B cGMP inhibited antibody