General Information

Product

RCE1 Antibody Affinity Purified

Description

Affinity Purified RCE1 homolog, prenyl protein peptidase Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid sequence 300-350 on human RCE1 protein.

Accession #

GenBank: AAH93726.1  

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9Y256

Overview

Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins.  Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B, and G-gamma-1.

Molecular Function

Hydrolase

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane

Structure

Ubiquitous

Alternative Nomenclature

CAAX prenyl protease 2 antibody

FACE2 antibody

Farnesylated proteins converting enzyme 2 antibody

Prenyl protein specific endoprotease 2 antibody

RCE1 homolog prenyl protein peptidase antibody

RCE1A antibody

RCE1B antibody

General Information

Product

SEC23 Antibody

Description

Affinity Purified Protein transfer protein Sec23A Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Drosophila melanogaster, Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 700-765 on human SEC23A protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:350

Western Blot

1:500

Protein

Uniprot #

Q15436

Overview

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.

Molecular Function

ER to Golgi vesicle-mediated transport; Intracellular protein transport; Zinc ion binding

Subcellular Location

COPII vesicle coat; Cytoplasm; Endoplasmic Reticulum Membrane; Golgi Apparatus Membrane; Peripheral Membrane Protein

Structure

COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1. Interacts with SEC23IP. Interacts with HTR4. Interacts with SLC6A4. Interacts with SEC16A.

Alternative Nomenclature

CLSD antibody

Protein transport protein Sec23A antibody

SEC23-related protein A antibody

General Information

Product

SEC24A Antibody

Description

Affinity Purified Protein transport protein Sec24A Antibody

Verified Applications

CM, ELISA, ICC/IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 810-850 on SEC24A protein.

Accession #

NCBI:  NP_001099250.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61-0.64 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

D3ZZA8

Molecular Function

Zinc ion bonding

Alternative Nomenclature

protein transport protein Sec24A antibody

SEC24 related gene family member A antibody

SEC24 related protein A antibody

SEC24 S cerevisiae related gene family member A antibody

General Information

Product

SEC24B Antibody

Description

Affinity Purified Protein transport protein Sec24B Antibody

Verified Applications

CM, ELISA, ICC, IHC, IF, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 390-430 on Sec24B protein.

Accession #

NCBI:  NP_001099944.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

D3ZW15

Molecular Function

Zinc ion bonding

Alternative Nomenclature

Protein transport protein Sec24B antibody

SC24B_HUMAN antibody

SEC24 family, member B (S. cerevisiae) antibody

SEC24 related gene family, member B antibody

SEC24-related protein B antibody

secretory protein 24 antibody

General Information

Product

SEC24C Antibody

Description

Affinity Purified Protein transport protein Sec24C Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 950-1000 on rat SEC24C protein.

Accession #

NCBI:  NP_001102926.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

B5DEG8

Molecular Function

Zinc ion bonding

Alternative Nomenclature

Protein transport protein Sec24C antibody

SC24C antibody

SC24C_HUMAN antibody

Sec 24C antibody

SEC24 related gene family, member C (S. cerevisiae) antibody

SEC24 related protein C antibody

General Information

Product

SEC24D Antibody

Description

Affinity Purified Sec24d protein Antibody

Verified Applications

CM, ELISA, ICC, IHC, IF, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Predicted:  Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 860-920 on human SEC24D protein.

Accession #

NCBI:  NP_055637

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

Dot Blot

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

O94855

Molecular Function

Zinc ion bonding

Alternative Nomenclature

KIAA0755 antibody

Protein transport protein Sec24D antibody

SEC24 family member D antibody

SEC24 related gene family, member D antibody

SEC24-related protein D antibody

General Information

Product

Alpha SNAP Antibody

Description

Affinity Purified alpha-soluble NSF attachment protein Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Pig, Rat

Immunogen

Synthetic peptide taken within amino acid region 195-245 on human alpha-soluble NSF attachment protein.

Accession #

GenBank: AAC80170.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.56 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P54920

Overview

Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

Molecular Function

Soluble NSF attachment protein activity; Syntaxin binding

Subcellular Location

Membrane, peripheral membrane protein

Structure

Interacts with PRKCABP, and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. Found in a complex with VAMP8. Component of a SNARE-like complex.

Alternative Nomenclature

Alpha soluble NSF attachment protein antibody

N ethylmaleimide sensitive factor attachment protein alpha antibody

NAPA antibody

SNAP alpha antibody

SNAPA antibody

General Information

Product

SorLA Antibody

Description

Affinity Purified Sortilin-related receptor Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 2100-2200 on human SORLA receptor protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.62 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

O88307

Overview

Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. May play a role in neural organization, as well as the establishment of embryonic organ systems.

Molecular Function

beta-amyloid binding, low-density lipoprotein particle binding

Subcellular Location

membrane, single-pass type I membrane protein, golgi apparatus, secreted

Expression

Abundant in brain, where it is mainly expressed in adult cerebellum, hippocampal ca regions, dentate gyrus, and to a much lesser extent in the cerebral cortex. Detectable in kidney, skeletal muscle, lung and spleen, but not in the liver.

Alternative Nomenclature

C11orf32 antibody

gp250 antibody

LDLR relative with 11 ligand binding repeats antibody

Low-density lipoprotein receptor relative with 11 ligand-binding repeats antibody

LR11 antibody

LRP9 antibody

Mosaic protein LR11 antibody

SORL1 antibody

SorLA 1 antibody

Sortilin related receptor antibody

Sorting protein related receptor containing LDLR class A repeats antibody

Sorting protein-related receptor containing

General Information

Product

Synaptoagmin 1 Antibody Affinity Purified

Description

Affinity Purified SYT1 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic  peptide taken within amino acid region 1-60 on SYT1 protein.

Accession #

GenBank: AAH58917.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P21579

Overview

May have regulatory rol in membrane interactions during trafficking of synaptic vesicles at active zones of synapse. Binds acidic phospholipids, can bind to at least three additional proteins in a CA2+ independent manner.

Molecular Function

1-phosphatidylinositol binding, calcium dependent phospholipid binding, calcium ion binding, low-density lipoprotein particle receptor binding, phosphatidylserine binding, transporter activity

Subcellular Location

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, single-pass membrane protein (Note: Synaptic vesicles and chromaffin granules.)

Alternative Nomenclature

P65 antibody

SVP65 antibody

Synaptotagmin 2 antibody

Synaptotagmin 1 antibody

SYT antibody

SYT1 antibody

Syt2 antibody

SytI antibody

General Information

Product

KIF13A Antibody

Description

Affinity Purified Kinesin-like protein KIF13A Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1700-1800 on human KIF13A isoform a protein.

Accession #

NCBI:  NP_071396.4

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.52 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9H1H9

Overview

Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis.

Molecular Function

Motor protein

Subcellular Location

Cytoplasm, Cytoskeleton, Endosome, Golgi apparatus, Membrane, Microtubule

Expression

highest levels in heart, brain and skeletal muscle

Structure

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

Alternative Nomenclature

bA500C11.2 antibody

FLJ27232 antibody

Homolog of mouse KIF13A mannose 6 phosphate receptor transporter antibody

KIF 13A antibody

Kinesin family member 13A antibody

Kinesin like protein KIF13A antibody

Kinesin like protein RBKIN antibody

RBKIN antibody