ITCH / AIP4 Antibody FITC

General Information

Product

ITCH / AIP4 Antibody FITC-Conjugated

Description

FITC-Conjugated ITCH protein Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-300 human ITCH protein.

Accession #

GenBank: AAH11571.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.66 µg/µl in antibody stabilization buffer

Form

FITC-Conjugated

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q96J02

Overview

Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It catalyzes 'Lys-29'-, 'Lys-48'- and 'Lys-63'-linked ubiquitin conjugation. It is involved in the control of inflammatory signaling pathways.

Subcellular Location

Cell membrane, cytoplasm, nucleus (Note: Associates with endocytic vesicles. May be recruited to exosomes by NDFIP1)

Expression

Widely expressed

Alternative Nomenclature

AIF4 antibody

AIP4 antibody

Atrophin 1 interacting protein 4 antibody

dJ468O1.1 antibody

E3 ubiquitin-protein ligase Itchy homolog antibody

EC 6.3.2 antibody

Itch antibody

Itchy E3 ubiquitin protein ligase antibody

NAPP1 antibody

NFE2 associated polypeptide 1 antibody

Ubiquitin protein ligase ITCH antibody