ITCH / AIP4 Positive Control

Product no.: PC-ITCH

$200.00

General Information
Product	ITCH / AIP4 Positive Control
Verified Applications	WB
Immunogen	Purified Protein
Accession #	GenBank: AAH11571.1
Physical Properties
Quantity	5 Applications
Volume	Inquire
Form	Western Blot Positive Control
Storage	-20⁰C for long term storage
Application Protocol
Western Blot	1:500
Protein
Uniprot #	Q96J02
Overview	Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It catalyzes 'Lys-29'-, 'Lys-48'- and 'Lys-63'-linked ubiquitin conjugation. It is involved in the control of inflammatory signaling pathways.
Subcellular Location	Cell membrane, cytoplasm, nucleus (Note: Associates with endocytic vesicles. May be recruited to exosomes by NDFIP1)
Expression	Widely expressed
Alternative Nomenclature	AIF4 antibody AIP4 antibody Atrophin 1 interacting protein 4 antibody dJ468O1.1 antibody E3 ubiquitin-protein ligase Itchy homolog antibody EC 6.3.2 antibody Itch antibody Itchy E3 ubiquitin protein ligase antibody NAPP1 antibody NFE2 associated polypeptide 1 antibody Ubiquitin protein ligase ITCH antibody

Protein information supplied by UniProt