ITCH / AIP4 Positive Control

General Information

Product

ITCH / AIP4 Positive Control

Verified Applications

WB

Immunogen

Purified Protein

Accession #

GenBank: AAH11571.1

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

Q96J02

Overview

Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It catalyzes 'Lys-29'-, 'Lys-48'- and 'Lys-63'-linked ubiquitin conjugation. It is involved in the control of inflammatory signaling pathways.

Subcellular Location

Cell membrane, cytoplasm, nucleus (Note: Associates with endocytic vesicles. May be recruited to exosomes by NDFIP1)

Expression

Widely expressed

Alternative Nomenclature

AIF4 antibody

AIP4 antibody

Atrophin 1 interacting protein 4 antibody

dJ468O1.1 antibody

E3 ubiquitin-protein ligase Itchy homolog antibody

EC 6.3.2 antibody

Itch antibody

Itchy E3 ubiquitin protein ligase antibody

NAPP1 antibody

NFE2 associated polypeptide 1 antibody

Ubiquitin protein ligase ITCH antibody