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General Information
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Product
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ITCH / AIP4 Peptide
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Description
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Antigenic Blocking Peptide ITCH protein
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 250-300 human ITCH protein.
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Accession #
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GenBank: AAH11571.1
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q96J02
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Overview
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Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It catalyzes 'Lys-29'-, 'Lys-48'- and 'Lys-63'-linked ubiquitin conjugation. It is involved in the control of inflammatory signaling pathways.
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Subcellular Location
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Cell membrane, cytoplasm, nucleus (Note: Associates with endocytic vesicles. May be recruited to exosomes by NDFIP1)
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Expression
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Widely expressed
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Alternative Nomenclature
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AIF4 antibody
AIP4 antibody
Atrophin 1 interacting protein 4 antibody
dJ468O1.1 antibody
E3 ubiquitin-protein ligase Itchy homolog antibody
EC 6.3.2 antibody
Itch antibody
Itchy E3 ubiquitin protein ligase antibody
NAPP1 antibody
NFE2 associated polypeptide 1 antibody
Ubiquitin protein ligase ITCH antibody
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ITCH / AIP4 Antibody
ITCH / AIP4 Antibody FITC
ITCH / AIP4 Antibody BIOTIN
ITCH / AIP4 Positive Control
