41 - 50 of 58 results

Lactase (LCT) Antibody

Product no.: LACT-101AP

$320.00

Description
Publications

General Information
Product	LCT Antibody
Description	Affinity Purified Lactase Antibody
Verified Applications	CM, ELISA, ICC, IF, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 1080-1130 on rat Lactase protein.
Accession #	GenBank: EDM09876.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.65-0.87 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:50
DB	1:10,000
ELISA	1:10,000
Immunocytochemistry	1:50
Immunofluorescence	1:50
Immunohistochemistry	1:50
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	UPI000154E3A5
Overview	LPH splits lactose in the small intestine.
Molecular Function	Glycosylceramidase activity; lactase activity
Subcellular Location	Apical cell membrane; Single-pass type I membrane protein
Expression	Intestine
Structure	The sequence exhibits 4 regions (I-IV) of internal homology; therefore LPH might have evolved by two cycles of partial gene duplication.
Alternative Nomenclature	LAC antibody Lactase antibody Lactase phlorizin hydrolase 1 antibody Lactase-glycosylceramidase antibody Lct antibody LPH antibody LPH1 antibody Phlorizin hydrolase antibody

Protein information supplied by UniProt

Accessories

Product

Note

Status

Price

LCT Antibody FITC

LACT-FITC

$375.00 *

LCT Antibody BIOTIN

LACT-BIOTIN

$375.00 *

LCT Blocking Peptide

P-LACT

$155.00 *

LCT Positive Control

PC-LACT

$200.00 *

Shipping Options

Bulk and Special Orders Quote

Display accessory details

Browse these categories as well: Metabolism & Homeostasis, Hypoxia, Growth Factors & Hormones, Energy Metabolism, Primaries

ENPP2 Antibody

Product no.: ATX-101AP

$285.00

Shipping Options

Bulk and Special Orders Quote

Description

General Information
Product	ENPP2 Antibody
Description	Affinity Purified ectonucleotide pyrophosphatase/phosphodiesterase 2 (Autotaxin) Antibody C-epitope
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Monkey, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 778-818 on human Ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) protein.
Accession #	GenBank: EAW91988.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.75-0.95 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	C-epitope
Storage	-20⁰C for long term storage
Application Protocol
Dot Blot	1:10,000
ELISA	1:10,000
Immunohistochemistry	1:50-1:150
Immunoprecipitation	1:200
Western Blot	1:250
Protein
Uniprot #	UPI0000EE3297
Overview	Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.
Molecular Function	alkylglycerophosphoethanolamine phosphodiesterase activity; calcium ion binding; hydrolase activity; lysophospholipase activity; nucleic acid binding; nucleotide diphosphatase activity; phosphodiesterase I activity; polysaccharide binding; scavenger receptor activity; transcription factor binding; zinc ion binding
Subcellular Location	Secreted
Expression	Predominantly expressed in brain, placenta, ovary, and small intestine. Expressed in a number of carcinomas such as hepatocellular and prostate carcinoma, neuroblastoma and non-small-cell lung cancer. Expressed in body fluids such as plasma, cerebral spinal fluid (CSF), saliva, follicular and amniotic fluids. Not detected in leukocytes. Isoform 1 is more highly expressed in peripheral tissues than in the central nervous system (CNS). Adipocytes only express isoform 1. Isoform 3 is more highly expressed in the brain than in peripheral tissues.
Structure	Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. Contains 2 SMB (somatomedin-B) domains.
Alternative Nomenclature	ATX antibody ATX X antibody Autotaxin antibody Autotaxin t antibody Ectonucleotide pyrophosphatase/phosphodiesterase 2 antibody Enpp2 antibody Extracellular lysophospholipase D antibody FLJ26803 antibody LysoPLD antibody NPP2 antibody PD IALPHA antibody PDNP2 antibody Phosphodiesterase I alpha antibody Plasma lysophospholipase D antibody

Protein information supplied by UniProt

Accessories

Product

Note

Status

Price

ENPP2 Antibody FITC

ATX-FITC

$375.00 *

ENPP2 Antibody BIOTIN

ATX-BIOTIN

$375.00 *

ENPP2 Blocking Peptide

P-ATX

$155.00 *

ENPP2 Positive Control

PC-ATX

$200.00 *

Shipping Options

Bulk and Special Orders Quote

Display accessory details

Browse these categories as well: Lipids, Cardiology, Metabolism & Homeostasis, Energy Metabolism, Angiogenesis, Neurodegenerative Disease, Cancer Research, Metabolism, Tumor Biomarkers, Primaries

SGLT1 Antibody

Product no.: SGLT-112AP

$285.00

Shipping Options

Bulk and Special Orders Quote

General Information
Product	SGLT1 Antibody
Description	Affinity Purified Sodum/glucose cotransporter 1 Antibody C-epitope
Verified Applications	CM, Dot Blot, ELISA, ICC, IF, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Monkey, Mouse, Rat, Sheep
Immunogen	Synthetic peptide corresponding to amino acids 603-623 of Human SGLT1.
Accession #	NCBI: NP_000334.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.55 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	C-epitope
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:250
DB	1:4,000
ELISA	1:4,000
Immunocytochemistry	1:250
Immunofluorescence	1:250
Immunohistochemistry	1:250
Immunoprecipitation	1:200
Western Blot	1:500-1:1,000
Protein
Uniprot #	P13866
Overview	Actively transports glucose into cells by Na+ cotransport with a Na+ to glucose coupling ratio of 2:1.
Molecular Function	glucose:sodium symporter activity
Subcellular Location	Membrane
Expression	Expessed mainly in intestine and kidney.
Structure	Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
Alternative Nomenclature	D22S675 antibody High affinity sodium glucose cotransporter 1 antibody Human Na+/glucose cotransporter 1 antibody Na(+)/glucose cotransporter 1 antibody NAGT antibody SGLT1 antibody SLC5A1 antibody Sodium glucose cotransporter 1 antibody Solute carrier family 5 member 1 antibody

Protein information supplied by UniProt

To view the Specification Sheet for SGLT1 Antibody, please click the link below:

SGLT1 Antibody | FabGennix

A customer wants to know that this product is specific to SGLT1 (That is not reacted with SGLT2). Is this product tested in being specific to SGLT1? If you have tested data, please send me. Or if not data, could you tell me something proving to be specific to SGLT1?
We would like to know whether SGLT1 Positive Control (PC-SGLT) are developed from insect sources or baculovirus expression systems.
I'm currently working on 5 different breast cancer cell lines and I'm using yours standard protocol for WB in that particular Antibodies, with 40ug of protein instead 60 (I have less nonspecific bands). My WB shows the band at approx. 58kDa in each cell line. I've checked UniProt database for SGLT1 and indeed there are 2 isoforms of this protein. The difference is about 120aas on the beginning of the protein sequence. I'm just curious why my antibodies recognizes only one isoform (the shorter protein) instead of two though the immunogen covers the opposite end of SGLT1 sequence (C-terminus) presents in both isoforms. For now, I'm pretty confused what protein I see in my WB.

A customer wants to know that this product is specific to SGLT1 (That is not reacted with SGLT2). Is this product tested in being specific to SGLT1? If you have tested data, please send me. Or if not data, could you tell me something proving to be specific to SGLT1?
1. Our SGLT1 antibodies, SGLT-101AP and SGLT-112AP, are epitope specific antibodies. They are raised against synthetic peptides that are unique to the SGLT1 protein and are not present in SGLT2. These antibodies do not react to random peptide in ELISA and in Dot Blot assays. These antibodies are affinity purified on immobilized antigen based affinity chromatography. Based on these observations, they will not cross react with SGLT2 proteins.
We would like to know whether SGLT1 Positive Control (PC-SGLT) are developed from insect sources or baculovirus expression systems.
1. SGLT1 Positive Control (PC-SGLT1.m and PC-SGLT.C) are not obtained from insect sells, SF9 cells or other cells. It is a partially purified protein obtained from normal enterocytes. The preparation is in SDS-Sample buffer and does not contain any preservatives. The shelf life is 1 year at -20⁰C and 6 months at 4⁰C.
I'm currently working on 5 different breast cancer cell lines and I'm using yours standard protocol for WB in that particular Antibodies, with 40ug of protein instead 60 (I have less nonspecific bands). My WB shows the band at approx. 58kDa in each cell line. I've checked UniProt database for SGLT1 and indeed there are 2 isoforms of this protein. The difference is about 120aas on the beginning of the protein sequence. I'm just curious why my antibodies recognizes only one isoform (the shorter protein) instead of two though the immunogen covers the opposite end of SGLT1 sequence (C-terminus) presents in both isoforms. For now, I'm pretty confused what protein I see in my WB.
1. We have two epitope specific antibodies to SGLT1. The antibody SGLT-101AP is a N-epitope (with respect to the other epitope) and SGLT-112AP is a C-epitope downstream from the SGLT-101AP. Both antibodies were tested on intestinal brush boarder membranes (BBM) and appears to label the high MW isoform of SGLT1. We did not see the smaller variant of SGLT1 in BBM. It is possible that smaller variant is abundant in breast cancer cells and high MW variant is not expressed in these cells. These observations yet to be confirmed using PC-SGLT1 samples or using recombinant SGLT1 proteins and compare them with renal BBM and intestinal BBM samples.

Customer ratings for SGLT1 Antibody

Number of ratings: 1
Average rating: 5

Excellent
from Verified Customer on 12/11/2020

Excellent results in Immunohistochemistry using mouse kidney tissue. 1/350 primary antibody dilution for 16 hours.

All incoming ratings are posted by actual shop visitors / webshop customers and their content is checked by the operator by means of a visual inspection.

Accessories

Product

Note

Status

Price

SGLT1 Antibody FITC

SGLT.c-FITC

$375.00 *

SGLT1 Antibody BIOTIN

SGLT.c-BIOTIN

$375.00 *

SGLT1 Blocking Peptide

P-SGLT.c

$155.00 *

SGLT1 Positive Control

PC-SGLT

$200.00 *

Shipping Options

Bulk and Special Orders Quote

Display accessory details

We also recommend

SGLT-101AP

SGLT1 Antibody

$285.00 *

SGLT2-201AP

SGLT2 Antibody

$285.00 *

Shipping Options

Bulk and Special Orders Quote

Browse these categories as well: Channels & Transporters, Plasma Membrane, Energy Metabolism, Metabolism, Primaries

SGLT1 Antibody

Product no.: SGLT-101AP

$285.00

Shipping Options

Bulk and Special Orders Quote

General Information
Product	SGLT1 Antibody
Description	Affinity Purified Sodum/glucose cotransporter 1 Antibody Mid-Region
Verified Applications	CM, Dot Blot, ELISA, ICC, IF, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human
Immunogen	Synthetic peptide corresponding to amino acids 402-422 of Human SGLT1.
Accession #	NCBI: NP_000334.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.6 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	Mid-Region
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:250
DB	1:4,000
ELISA	1:4,000
Immunocytochemistry	1:250
Immunofluorescence	1:250
Immunohistochemistry	1:250
Immunoprecipitation	1:200
Western Blot	1:500-1:1,000
Protein
Uniprot #	P13866
Overview	Actively transports glucose into cells by Na+ cotransport with a Na+ to glucose coupling ratio of 2:1.
Molecular Function	glucose:sodium symporter activity
Subcellular Location	Membrane
Expression	Expessed mainly in intestine and kidney.
Structure	Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
Alternative Nomenclature	D22S675 antibody High affinity sodium glucose cotransporter 1 antibody Human Na+/glucose cotransporter 1 antibody NAGT antibody SGLT 1 antibody SLC5A1 antibody Sodium glucose cotransporter 1 antibody Solute carrier family 5 member 1 antibody

Protein information supplied by Uniprot

To view the Specification Sheet for SGLT1 Antibody, please click the link below:

SGLT1 Antibody | FabGennix

A customer wants to know that this product is specific to SGLT1 (That is not reacted with SGLT2). Is this product tested in being specific to SGLT1? If you have tested data, please send me. Or if not data, could you tell me something proving to be specific to SGLT1?
We would like to know whether SGLT1 Positive Control (PC-SGLT) are developed from insect sources or baculovirus expression systems.
I'm currently working on 5 different breast cancer cell lines and I'm using yours standard protocol for WB in that particular Antibodies, with 40ug of protein instead 60 (I have less nonspecific bands). My WB shows the band at approx. 58kDa in each cell line. I've checked UniProt database for SGLT1 and indeed there are 2 isoforms of this protein. The difference is about 120aas on the beginning of the protein sequence. I'm just curious why my antibodies recognizes only one isoform (the shorter protein) instead of two though the immunogen covers the opposite end of SGLT1 sequence (C-terminus) presents in both isoforms. For now, I'm pretty confused what protein I see in my WB.

A customer wants to know that this product is specific to SGLT1 (That is not reacted with SGLT2). Is this product tested in being specific to SGLT1? If you have tested data, please send me. Or if not data, could you tell me something proving to be specific to SGLT1?
1. Our SGLT1 antibodies, SGLT-101AP and SGLT-112AP, are epitope specific antibodies. They are raised against synthetic peptides that are unique to the SGLT1 protein and are not present in SGLT2. These antibodies do not react to random peptide in ELISA and in Dot Blot assays. These antibodies are affinity purified on immobilized antigen based affinity chromatography. Based on these observations, they will not cross react with SGLT2 proteins.
We would like to know whether SGLT1 Positive Control (PC-SGLT) are developed from insect sources or baculovirus expression systems.
1. SGLT1 Positive Control (PC-SGLT1.m and PC-SGLT.C) are not obtained from insect sells, SF9 cells or other cells. It is a partially purified protein obtained from normal enterocytes. The preparation is in SDS-Sample buffer and does not contain any preservatives. The shelf life is 1 year at -20⁰C and 6 months at 4⁰C.
I'm currently working on 5 different breast cancer cell lines and I'm using yours standard protocol for WB in that particular Antibodies, with 40ug of protein instead 60 (I have less nonspecific bands). My WB shows the band at approx. 58kDa in each cell line. I've checked UniProt database for SGLT1 and indeed there are 2 isoforms of this protein. The difference is about 120aas on the beginning of the protein sequence. I'm just curious why my antibodies recognizes only one isoform (the shorter protein) instead of two though the immunogen covers the opposite end of SGLT1 sequence (C-terminus) presents in both isoforms. For now, I'm pretty confused what protein I see in my WB.
1. We have two epitope specific antibodies to SGLT1. The antibody SGLT-101AP is a N-epitope (with respect to the other epitope) and SGLT-112AP is a C-epitope downstream from the SGLT-101AP. Both antibodies were tested on intestinal brush boarder membranes (BBM) and appears to label the high MW isoform of SGLT1. We did not see the smaller variant of SGLT1 in BBM. It is possible that smaller variant is abundant in breast cancer cells and high MW variant is not expressed in these cells. These observations yet to be confirmed using PC-SGLT1 samples or using recombinant SGLT1 proteins and compare them with renal BBM and intestinal BBM samples.

Customer ratings for SGLT1 Antibody

Number of ratings: 1
Average rating: 5

Excellent
from Verified Customer on 12/10/2020

Excellent staining in Western blot using mouse tissue lysate- whole (cortex). 1/1,000 primary antibody dilution in .1% BSA.

All incoming ratings are posted by actual shop visitors / webshop customers and their content is checked by the operator by means of a visual inspection.

Accessories

Product

Note

Status

Price

SGLT1 Antibody FITC

SGLT.m-FITC

$375.00 *

SGLT1 Antibody BIOTIN

SGLT.m-BIOTIN

$375.00 *

SGLT1 Blocking Peptide

P-SGLT.m

$155.00 *

SGLT1 Positive Control

PC-SGLT

$200.00 *

Shipping Options

Bulk and Special Orders Quote

Display accessory details

We also recommend

SGLT2-201AP

SGLT2 Antibody

$285.00 *

SGLT-112AP

SGLT1 Antibody

$285.00 *

Shipping Options

Bulk and Special Orders Quote

Browse these categories as well: Channels & Transporters, Plasma Membrane, Energy Metabolism, Metabolism, Primaries

Soluble Adenylate Cyclase 1 Antibody

Product no.: SAC-112AP

$320.00

Shipping Options

Bulk and Special Orders Quote

Description
Publications

General Information
Product	Soluble Adenylate Cyclase 1 Antibody
Description	Affinity Purified Soluble adenylyl cyclase brain isoform, partial Antibody Mid-Region
Verified Applications	CM, ELISA, ICC, IHC, IF, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide corresponding to unique amino acid sequence on SAC protein.
Accession #	GenBank: ACA47266.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	Mid-Region
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:200
DB	1:10,000
ELISA	1:10,000
Immunocytochemistry	1:200
Immunofluorescence	1:200
Immunohistochemistry	1:200
Western Blot	1:500
Protein
Uniprot #	B1PMG2
Molecular Function	adenylate cyclase activity
Subcellular Location	Cytoplasm, membrane
Alternative Nomenclature	Adcy1 antibody adenyl cyclase antibody ATP pyrophosphate lyase antibody Brain adenylate cyclase 1 antibody Ca(2+)/calmodulin-activated adenylyl cyclase antibody

Protein information supplied by UniProt

Accessories

Product

Note

Status

Price

Soluble Adenylate Cyclase 1 Antibody FITC

SAC.112-FITC

$375.00 *

Soluble Adenylate Cyclase 1 Antibody BIOTIN

SAC.112-BIOTIN

$375.00 *

Soluble Adenylate Cyclase 1 Blocking Peptide

P-SAC.112

$155.00 *

Soluble Adenylate Cyclase 1 Positive Control

PC-SAC

$220.00 *

Shipping Options

Bulk and Special Orders Quote

Display accessory details

We also recommend

SAC-101AP

Soluble Adenylate Cyclase 1 Antibody

$320.00 *

SAC-121AP

Soluble Adenylate Cyclase 1 Antibody

$320.00 *

SAC10-101AP

Adenylate Cyclase 10 Antibody

$285.00 *

Shipping Options

Bulk and Special Orders Quote

Browse these categories as well: G-Protein Coupled Receptors, Adenylate Cyclases, Regulation, Neurotransmission, Metabolism, Energy Metabolism, Primaries

Soluble Adenylate Cyclase 1 Antibody

Product no.: SAC-121AP

$320.00

Shipping Options

Bulk and Special Orders Quote

Description
Publications

General Information
Product	Soluble Adenylate Cyclase 1 Antibody
Description	Affinity Purified Soluble adenylyl cyclase brain isoform, partial Antibody C-epitope
Verified Applications	CM, ELISA, ICC, IHC, IF, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide corresponding to unique amino acid sequence on SAC protein.
Accession #	GenBank: ACA47266.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	C-epitope
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:200
DB	1:10,000
ELISA	1:10,000
Immunocytochemistry	1:200
Immunofluorescence	1:200
Immunohistochemistry	1:200
Western Blot	1:500
Protein
Uniprot #	B1PMG2
Molecular Function	adenylate cyclase activity
Subcellular Location	Cytoplasm, membrane
Alternative Nomenclature	Adcy1 antibody adenyl cyclase antibody ATP pyrophosphate lyase antibody Brain adenylate cyclase 1 antibody Ca(2+)/calmodulin-activated adenylyl cyclase antibody

Protein information supplied by UniProt

Accessories

Product

Note

Status

Price

Soluble Adenylate Cyclase 1 Antibody FITC

SAC.121-FITC

$375.00 *

Soluble Adenylate Cyclase 1 Antibody BIOTIN

SAC.121-BIOTIN

$375.00 *

Soluble Adenylate Cyclase 1 Blocking Peptide

P-SAC.121

$155.00 *

Soluble Adenylate Cyclase 1 Positive Control

PC-SAC

$220.00 *

Shipping Options

Bulk and Special Orders Quote

Display accessory details

We also recommend

SAC-101AP

Soluble Adenylate Cyclase 1 Antibody

$320.00 *

SAC-112AP

Soluble Adenylate Cyclase 1 Antibody

$320.00 *

SAC10-101AP

Adenylate Cyclase 10 Antibody

$285.00 *

Shipping Options

Bulk and Special Orders Quote

Browse these categories as well: G-Protein Coupled Receptors, Adenylate Cyclases, Regulation, Neurotransmission, Metabolism, Energy Metabolism, Primaries

Soluble Adenylate Cyclase 1 Antibody

Product no.: SAC-101AP

$320.00

Shipping Options

Bulk and Special Orders Quote

Description
Publications

General Information
Product	Soluble Adenylate Cyclase 1 Antibody
Description	Affinity Purified Soluble adenylyl cyclase brain isoform, partial Antibody N-epitope
Verified Applications	CM, ELISA, ICC, IHC, IF, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide corresponding to unique amino acid sequence on SAC protein.
Accession #	GenBank: ACA47266.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	N-epitope
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:200
DB	1:10,000
ELISA	1:10,000
Immunocytochemistry	1:200
Immunofluorescence	1:200
Immunohistochemistry	1:200
Western Blot	1:500
Protein
Uniprot #	B1PMG2
Molecular Function	adenylate cyclase activity
Subcellular Location	Cytoplasm, membrane
Alternative Nomenclature	Adcy1 antibody adenyl cyclase antibody ATP pyrophosphate lyase antibody Brain adenylate cyclase 1 antibody Ca(2+)/calmodulin-activated adenylyl cyclase antibody

Protein information supplied by UniProt

Accessories

Product

Note

Status

Price

Soluble Adenylate Cyclase 1 Antibody FITC

SAC.101-FITC

$375.00 *

Soluble Adenylate Cyclase 1 Antibody BIOTIN

SAC.101-BIOTIN

$375.00 *

Soluble Adenylate Cyclase 1 Blocking Peptide

P-SAC.101

$155.00 *

Soluble Adenylate Cyclase 1 Positive Control

PC-SAC

$220.00 *

Shipping Options

Bulk and Special Orders Quote

Display accessory details

We also recommend

SAC-112AP

Soluble Adenylate Cyclase 1 Antibody

$320.00 *

SAC-121AP

Soluble Adenylate Cyclase 1 Antibody

$320.00 *

SAC10-101AP

Adenylate Cyclase 10 Antibody

$285.00 *

Shipping Options

Bulk and Special Orders Quote

Browse these categories as well: G-Protein Coupled Receptors, Adenylate Cyclases, Regulation, Neurotransmission, Metabolism, Energy Metabolism, Primaries

LYK5 Antibody

Product no.: STRAD-112AP

$285.00

Shipping Options

Bulk and Special Orders Quote

Description

General Information
Product	LYK5 Antibody
Description	Affinity Purified STE20-related kinase adapter protein alpha Antibody C-epitope
Verified Applications	ELISA, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Monkey
Immunogen	Synthetic peptide taken within amino acid region 381-431 on human STE-20 related kinase adapter protein alpha.
Accession #	NCBI: NP_001003787.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.64-0.72 µg/µl in antibody stabilization buffer
Immunoglobulin	IgG
Form	Affinity Purified
Clonality	Polyclonal
Determinant	C-epitope
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunoprecipitation	1:150
Western Blot	1:500
Protein
Uniprot #	Q7RTN6
Overview	Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.
Molecular Function	ATP Binding, protein kinase activator activity, kinase binding, transferase activity, transferring phosphorus-containing groups
Subcellular Location	Nucleus, cytoplasm
Expression	Expressed in liver
Structure	Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. Contains 1 protein kinase domain.
Alternative Nomenclature	Protein kinase LYK5 antibody Serologically defined breast cancer antigen NY BR 96 antibody STE20 related adapter protein antibody STRAD alpha antibody STRAD antibody

Protein information supplied by UniProt

Accessories

Product

Note

Status

Price

LYK5 Antibody FITC

STRAD.112-FITC

$375.00 *

LYK5 Antibody BIOTIN

STRAD.112-BIOTIN

$375.00 *

LYK5 Blocking Peptide

P-STRAD.112

$155.00 *

LYK5 Positive Control

PC-STRAD

$200.00 *

Shipping Options

Bulk and Special Orders Quote

Display accessory details

We also recommend

STRAD-101AP

LYK5 Antibody

$285.00 *

CAB39-101AP

CAB39 Antibody

$285.00 *

Shipping Options

Bulk and Special Orders Quote

Browse these categories as well: Cell Cycle, Cell Cycle, Kinase / Phosphatases, Tumor Associated, Tumor Biomarkers, Energy Metabolism, Metabolism, Primaries

LYK5 Antibody

Product no.: STRAD-101AP

$285.00

Shipping Options

Bulk and Special Orders Quote

Description
Specification Sheet

General Information
Product	LYK5 Antibody
Description	Affinity Purified STE20-related kinase adapter protein alpha Antibody N-epitope
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Monkey
Immunogen	Synthetic peptide taken within amino acid region 50-100 on human STE-20 related kinase adapter protein alpha.
Accession #	NCBI: NP_001003787.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.64-0.72 µg/µl in antibody stabilization buffer
Immunoglobulin	IgG
Form	Affinity Purified
Clonality	Polyclonal
Determinant	N-epitope
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunohistochemistry	1:50-1:150
Immunoprecipitation	1:150
Western Blot	1:500
Protein
Uniprot #	Q7RTN6
Overview	Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.
Molecular Function	ATP Binding, protein kinase activator activity, kinase binding, transferase activity, transferring phosphorus-containing groups
Subcellular Location	Nucleus, cytoplasm
Expression	Expressed in liver
Structure	Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. Contains 1 protein kinase domain.
Alternative Nomenclature	Protein kinase LYK5 antibody Serologically defined breast cancer antigen NY BR 96 antibody STE20 related adapter protein antibody STRAD alpha antibody STRAD antibody

Protein information supplied by UniProt

Accessories

Product

Note

Status

Price

LYK5 Antibody FITC

STRAD.101-FITC

$375.00 *

LYK5 Antibody BIOTIN

STRAD.101-BIOTIN

$375.00 *

LYK5 Blocking Peptide

P-STRAD.101

$155.00 *

LYK5 Positive Control

PC-STRAD

$200.00 *

Shipping Options

Bulk and Special Orders Quote

Display accessory details

We also recommend

STRAD-112AP

LYK5 Antibody

$285.00 *

CAB39-101AP

CAB39 Antibody

$285.00 *

Shipping Options

Bulk and Special Orders Quote

Browse these categories as well: Cell Cycle, Cell Cycle, Kinase / Phosphatases, Tumor Associated, Tumor Biomarkers, Energy Metabolism, Metabolism, Primaries

GSK3 beta Antibody

Product no.: GSK3B-301Y

$285.00

Shipping Options

Bulk and Special Orders Quote

Description
Specification Sheet

General Information
Product	GSK3 beta Antibody
Description	Affinity Purified Glycogen Synthase Kinase-3 beta Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Chicken
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 1-50 on human GSK3 beta protein.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.6 µg/µl in antibody stabilization buffer
Immunoglobulin	IgY
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunohistochemistry	1:100
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	P49841
Overview	Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. Requires primed phosphorylation of the majority of its substrates. In skeletal muscle, contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. May also mediate the development of insulin resistance by regulating activation of transcription factors. Regulates protein synthesis by controlling the activity of initiation factor 2B (EIF2BE/EIF2B5) in the same manner as glycogen synthase. In Wnt signaling, GSK3B forms a multimeric complex with APC, AXIN1 and CTNNB1/beta-catenin and phosphorylates the N-terminus of CTNNB1 leading to its degradation mediated by ubiquitin/proteasomes. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA.
Molecular Function	Developmental protein, Kinase, Serine/threonine-protein kinase, Signal tranduction inhibitor, Transferase
Subcellular Location	Cytoplasm; Nucleus; Cell membrane
Expression	Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney. Colocalizes with EIF2AK2/PKR and TAU in the Alzheimer disease (AD) brain.
Structure	Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily. Contains 1 protein kinase domain.
Alternative Nomenclature	Glycogen Synthase Kinase 3 Beta antibody GSK 3 beta antibody Serine/threonine-protein kinase GSK3B antibody

Protein information supplied by UniProt

Accessories

Product

Note

Status

Price

GSK3 beta Antibody FITC

GSK3B-Y-FITC

$375.00 *

GSK3 beta Antibody BIOTIN

GSK3B-Y-BIOTIN

$375.00 *

GSK3 beta Blocking Peptide

P-GSK3B-Y

$155.00 *

GSK3 beta Positive Control

PC-GSK3B

$200.00 *

Shipping Options

Bulk and Special Orders Quote

Display accessory details

We also recommend

Anti-Chicken Secondary Rabbit Anti-Chicken IgG HRP $150.00 *	SGK3-301Y SGK3 Antibody $285.00 *	SGK1-101Y SGK1 Antibody $285.00 *
SGK2-201Y SGK2 Antibody $285.00 *

Shipping Options

Bulk and Special Orders Quote

Browse these categories as well: Protein Kinases, Notch Pathway, Serine/Threonine Kinases, Wnt, Diabetes, Cardiology, Metabolism, Energy Metabolism, Atherosclerosis, Primaries, Chicken IgY Primaries

41 - 50 of 58 results

Terms and Conditions

Right of withdrawal

Shipping Options

Select your currency:

Rs.

AU$

	Fabgennix Soluble Adenylate Cyclase 1 Antibody has been used in 2 Publications
Imber, Ann N., et al. "A HCO 3−-dependent mechanism involving soluble adenylyl cyclase for the activation of Ca 2+ currents in locus coeruleus neurons." Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842.12 (2014): 2569-2578. PMID25092170		Immunohistochemistry; *Rat*
Li, Shimin, Kah Tan Allen, and Joseph A. Bonanno. "Soluble adenylyl cyclase mediates bicarbonate-dependent corneal endothelial cell protection." American Journal of Physiology-Cell Physiology 300.2 (2011): C368-C374. PMID21123735		Western Blot; *Mouse*

	Fabgennix Soluble Adenylate Cyclase 1 Antibody has been used in 2 Publications
Imber, Ann N., et al. "A HCO 3−-dependent mechanism involving soluble adenylyl cyclase for the activation of Ca 2+ currents in locus coeruleus neurons." Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842.12 (2014): 2569-2578. PMID25092170		Immunohistochemistry; *Rat*
Li, Shimin, Kah Tan Allen, and Joseph A. Bonanno. "Soluble adenylyl cyclase mediates bicarbonate-dependent corneal endothelial cell protection." American Journal of Physiology-Cell Physiology 300.2 (2011): C368-C374. PMID21123735		Western Blot; *Mouse*

	Fabgennix Soluble Adenylate Cyclase 1 Antibody has been used in 3 Publications
Xu, Mengda, et al. "Acetate attenuates inflammasome activation through GPR43-mediated Ca 2+-dependent NLRP3 ubiquitination." Experimental & molecular medicine 51.7 (2019): 83. PMID: 31337751		Immunoprecipitation, Western blot; *Mouse*
Imber, Ann N., et al. "A HCO 3−-dependent mechanism involving soluble adenylyl cyclase for the activation of Ca 2+ currents in locus coeruleus neurons." Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842.12 (2014): 2569-2578. PMID: 25092170		Immunohistochemistry; *Rat*
Li, Shimin, Kah Tan Allen, and Joseph A. Bonanno. "Soluble adenylyl cyclase mediates bicarbonate-dependent corneal endothelial cell protection." American Journal of Physiology-Cell Physiology 300.2 (2011). PMID: 21123735		Western Blot; *Mouse*

Home page Primary Antibodies Metabolism & Homeostasis Lactase (LCT) Antibody

Home page Primary Antibodies Cell Biology Lipids ENPP2 Antibody

Home page Primary Antibodies Channels & Transporters SGLT1 Antibody

Home page Primary Antibodies Channels & Transporters SGLT1 Antibody

Home page Primary Antibodies Signal Transduction G-Protein Coupled Receptors Soluble Adenylate Cyclase 1 Antibody

Home page Primary Antibodies Signal Transduction G-Protein Coupled Receptors Soluble Adenylate Cyclase 1 Antibody

Home page Primary Antibodies Signal Transduction G-Protein Coupled Receptors Soluble Adenylate Cyclase 1 Antibody

Home page Primary Antibodies Cancer Research Cell Cycle LYK5 Antibody

Home page Primary Antibodies Cancer Research Cell Cycle LYK5 Antibody

Home page Primary Antibodies Protein Kinases GSK3 beta Antibody

Lactase (LCT) Antibody

Accessories

ENPP2 Antibody

Accessories

SGLT1 Antibody

Customer ratings for SGLT1 Antibody

Accessories

We also recommend

SGLT1 Antibody

Customer ratings for SGLT1 Antibody

Accessories

We also recommend

Soluble Adenylate Cyclase 1 Antibody

Accessories

We also recommend

Soluble Adenylate Cyclase 1 Antibody

Accessories

We also recommend

Soluble Adenylate Cyclase 1 Antibody

Accessories

We also recommend

LYK5 Antibody

Accessories

We also recommend

LYK5 Antibody

Accessories

We also recommend

GSK3 beta Antibody

Accessories

We also recommend