General Information

Product

Netrin 1 Antibody Affinity Purified

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-300 on human Netrin-1 protein.

Accession #

NCBI: NP_004813.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.62-0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

O95631

Overview

Netrins control guidance of CNS commissural axons and peripheral motor axons; serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis;Involved in tumorigenesis by regulating apoptosis.

Subcellular Location

Extracellular matrix, Secreted

Expression

highest levels in heart, small intestine, colon, liver and prostate. Reduced expression in brain tumors and neuroblastomas. Expressed in epididymis (at protein level).

Alternative Nomenclature

epididymis tissue protein Li 131P antibody

Netrin 1, mouse, homolog of antibody

Netrin 1-like antibody

Ntn 1 antibody

Unc6 antibody

General Information

Product

p75 NGF Receptor Antibody

Description

Affinity Purified p75 neurotrophin receptor a-2 Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Immunogen

Synthetic peptide corresponding to unique N-terminus amino acid sequence on P-75NTR protein.

Accession #

GenBank: AAD51031.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.95 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9PRG7

Molecular Function

Receptor

Alternative Nomenclature

CD271 antibody

CD271 antigen antibody

Gp80 LNGFR antibody

Low affinity nerve growth factor receptor antibody

Nerve growth factor receptor antibody

NGF receptor antibody

NGFR antibody

p75 ICD antibody

p75 Neurotrophin receptor antibody

p75 NTR antibody

TNFR Superfamily Member 16 antibody

TNFRSF16 antibody

General Information

Product

proBNP Antibody

Description

Affinity Purified Gamma-brain natriuretic peptide Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 100-150 on human proBNP.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.8 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P16860

Overview

A cardiac hormone that may also serve as a paracrine antifibrotic factor in the heart.  Also functions in cardiovascular homeostasis via natriuresis, diuresis, vasorelaxation, and the inhibition of renin and aldosterone secretion.

Molecular Function

Diuretic hormone activity, Hormone, Vasoactive

Subcellular Location

Secreted

Expression

Is expressed in the brain and atria, however it is expressed at much lower levels than ANP.

Alternative Nomenclature

BNP 32 antibody

BNP antibody

BNP(1-32) antibody

BNP(5-29) antibody

Brain Natriuretic Peptide 32 antibody

Gamma brain natriuretic peptide antibody

Natriuretic peptide precursor type B antibody

NPPB antibody

General Information

Product

RASD2 Antibody

Description

Affinity Purified Ras homolog enriched in striatum Antibody

Verified Applications

ELISA, IHC ,IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-317 on RASD2 protein.

Accession #

GenBank: AAH36988.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Dot Blot

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:500

Western Blot

1:500-1:1,000

Protein

Uniprot #

Q8JZW1

Molecular Function

GTP binding

Alternative Nomenclature

GTP binding protein Rhes antibody

MGC:4834 antibody

Ras homolog enriched in striatum antibody

RASD 2 antibody

Rhes antibody

TEM2 antibody

Tumor endothelial marker 2 antibody

General Information

Product

TMEPAI Antibody

Description

Affinity Purified Prostate transmembrane protein, androgen induced 1 Antibody

Verified Applications

Dot Blot, ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Purified TMEPAI protein which was emulsified with adjuvants to acheive the desired antigenicity.

Accession #

NCBI:  NP_035719.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

.65-.694 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Western Blot

1:500-1:1,000

Protein

Uniprot #

D2KUZ7

Overview

May function as a negative regulator of TGF-beta signaling and thereby inhibits activin-mediated mesoderm formation.

Molecular Function

signal transduction inhibitor

Subcellular Location

Early endosome membrane; Single-pass membrane protein, Golgi apparatus membrane; Single-pass membrane protein

Alternative Nomenclature

PMEPA1 antibody

Prostate transmembrane protein, androgen induced 1 antibody

Solid tumor associated 1 protein antibody

STAG1 antibody

TMEPAI antibody

Transmembrane prostate androgen induced protein antibody

General Information

Product

TORC2 Antibody

Description

Affinity Purified CREB-regulated transcription coactivator 2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse

Immunogen

Synthetic peptide taken within amino acid region 640-693 on human CREB-regulated transcription coactivator 2 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q53ET0

Overview

Activator, cAMP response element binding protein binding

Subcellular Location

Cytoplasm, Nucleus

Expression

Most abundantly expressed in the thymus. Present in both B and T-lymphocytes. Highly expressed in HEK293T cells and in insulinomas. High levels also in spleen, ovary, muscle and lung, with highest levels in muscle.

Alternative Nomenclature

CREB regulated transcription coactivator 2 antibody

CRTC2 antibody

TORC-2 antibody

Transducer of CREB protein 2 antibody

Transducer of regulated cAMP response element-binding protein antibody

Immunoprecipitation

General Information

Product

TRAF6 Antibody Affinity Purified

Description

Affinity Purified TNF receptor-associated factor 6 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on TRAF6 protein.

Accession #

NCBI:  NP_665802.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9Y4K3

Overview

Mediates synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, may be essential for formation of functional osteoclasts, seems to also play a role in dendritic cells maturation and/or activation.

Molecular Function

histone deacetylase binding, ligase activity, zinc ion binding, protein kindase B binding, protein N-terminus binding signal transducer activity

Subcellular Location

Cytoplasm, cell cortex, nucleus, lipid droplet. (Note: Found in nuclei of some aggressive B-cell lymphoma cell lines as well as in the nuclei of both resting and activated T- and B-lymphocytes. Found in punctate nuclear body protein complexes. Ubiquitinat

Expression

Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Alternative Nomenclature

E3 ubiquitin-protein ligase TRAF6 antibody

Interleukin 1 signal transducer antibody

RING finger protein 85 antibody

RNF85 antibody

TNF receptor-associated factor 6, E3 ubiquitin protein ligase antibody

General Information

Product

UCN2 Antibody Affinity Purified

Description

Affinity Purified Urocortin-2 preprotein Antibody

Verified Applications

ELISA, SB, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken wtihin amino acid region 70-115 of human Urocortin 2 protein.

Accession #

NCBI:  NP_149976.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.71 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q96RP3

Overview

Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

Molecular Function

Hormone binding, receptor binding, hormone

Subcellular Location

Secreted

Expression

Binds with high affinity to CRF receptors 2-alpha and 2-beta.

Alternative Nomenclature

SRP

Stresscopin-related peptide

Ucn II

UCN2

UCNI

UR

Urocortin II

Urocortin-2

Urocortin-related peptide

URP

General Information

Product

TIE2 Antibody

Description

Affinity Purified Tyrosine-protein kinase receptor Tie-1 isoform 2 Antibody

Verified Applications

DB, ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 540-590 on human Tyrosine-protein kinase receptor Tie-1 isoform 2 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68-0.70 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q02763

Overview

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

Molecular Function

Kinase, Receptor, Transferase, Tyrosine-protein kinase

Subcellular Location

Integral component of membrane

Expression

Detected in umbilical vein endothelial cells. Proteolytic processing gives rise to a soluble extracellular domain that is detected in blood plasma (at protein level). Predominantly expressed in endothelial cells and their progenitors, the angioblasts. Has been directly found in placenta and lung, with a lower level in umbilical vein endothelial cells, brain and kidney.

Structure

Belongs to the protein kinase superfamily. Tyr protein kinase family.  Contains protein kinase domain.

Alternative Nomenclature

Angiopoietin 1 receptor antibody

CD202b antibody

Endothelial tyrosine kinase antibody

Endothelium specific receptor tyrosine kinase 2 antibody

Hyk antibody

p140 TEK antibody

TEK antibody

tek tyrosine kinase antibody

TIE 2 antibody

Tunica interna endothelial cell kinase antibody

Tyrosine kinase with Ig and EGF homology domains 2 antibody

Tyrosine protein kinase receptor TEK antibody

Tyrosine protein kinase receptor TIE 2 antibody

Venous malformations multiple cutaneous and mucosal antibody

VMCM 1 antibody

VMCM antibody

General Information

Product

Phospho Lyn Antibody Affinity Purified

Description

Affinity Purified Tyrosine-protein kinase Lyn isoform A Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Immunogen

Phosphorylated synthetic peptide taken within amino acid region 425-525 on human Lyn protein. Phospho Y 491.

Accession #

NCBI:  NP_002341

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P07948

Overview

Non-receptor tyrosine-protein kinase that plays role in regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic agents

Molecular Function

Kinase, Transferase, Tyrosine-protein kinase

Subcellular Location

Cell membrane, Cytoplasm, Golgi apparatus, Membrane, Nucleus

Expression

monocytes,placenta,fetal brain, lung, liver,kidney and epidermoid, hematopoietic, and neuronal cells,also primary neuroblastoma tumors

Structure

Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily

Alternative Nomenclature

AA407514 antibody

EC 2.7.10.2 antibody

FLJ26625 antibody

Hck 2 antibody

JTK 8 antibody

Lck/Yes related novel protein tyrosine kinase antibody

LYN antibody

LYN proto oncogene, Src family tyrosine kinase antibody

ONCOGENE LYN antibody

p53Lyn antibody

p56Lyn antibody

Tyrosine protein kinase LYN antibody

V yes 1 Yamaguchi sarcoma viral related oncogene homolog antibody