General Information

Product

ITCH / AIP4 Antibody

Description

Affinity Purified ITCH protein Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-300 human ITCH protein.

Accession #

GenBank: AAH11571.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.66 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q96J02

Overview

Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It catalyzes 'Lys-29'-, 'Lys-48'- and 'Lys-63'-linked ubiquitin conjugation. It is involved in the control of inflammatory signaling pathways.

Subcellular Location

Cell membrane, cytoplasm, nucleus (Note: Associates with endocytic vesicles. May be recruited to exosomes by NDFIP1)

Expression

Widely expressed

Alternative Nomenclature

AIF4 antibody

AIP4 antibody

Atrophin 1 interacting protein 4 antibody

dJ468O1.1 antibody

E3 ubiquitin-protein ligase Itchy homolog antibody

EC 6.3.2 antibody

Itch antibody

Itchy E3 ubiquitin protein ligase antibody

NAPP1 antibody

NFE2 associated polypeptide 1 antibody

Ubiquitin protein ligase ITCH antibody

General Information

Product

DRIP130 Antibody

Description

Affinity Purified MED23 protein Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic pepetide taken within amino acid region 650-700 on MED23 protein.

Accession #

GenBank: AAH60759.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9ULK4

Overview

Required for transcriptional activation subsequent to assembly of preinitiation complex. Component of mediator complex, mediator functions as a bridge to convey information from gene specific regulatory proteins to basal RNA polymerase II transcription machinery.

Molecular Function

Transcription coactivator activity

Subcellular Location

Nucleus

Alternative Nomenclature

130 kDa transcriptional co activator antibody

ARC 130 antibody

Cofactor required for Sp1 transcriptional activation subunit 3 130kDa antibody

CRSP 130 antibody

CRSP 133 antibody

DRIP 130 antibody

KIAA1216 antibody

MED 23 antibody

SUR 2 antibody

Vitamin D3 receptor interacting protein antibody

General Information

Product

MEDEA Antibody Affinity Purified

Description

Affinity Purified Medea Antibody

Verified Applications

DB, ELISA, WB

Host

Rabbit

Species Cross Reactivity

Drosophila melanogaster

Immunogen

Synthetic peptide taken within amino acid region 150-250 on Drosophila melanogaster Medea protein.

Accession #

GenBank: AAC62005.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.73 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Western Blot

1:500-1:750

Protein

Uniprot #

Q7KPL1

Overview

Sequence-specific DNA binding transcription factor activity

Molecular Function

Transforming growth factor beta receptor, common-partner cytoplasmic mediator activity

Subcellular Location

Cytoplasm;Nucleus

Structure

Belongs to the dwarfin/SMAD family.

Alternative Nomenclature

(Small) Mothers Against Decapentaplegic antibody

Deleted in Pancreatic Carcinoma 4 antibody

DPC 4 antibody

hSMAD4 antibody

JIP antibody

MAD mothers against decapentaplegic homolog 4 antibody

MADH 4 antibody

Med antibody

Medea antibody

MYHRS antibody

Smad 4 antibody

General Information

Product

NM23A Antibody Affinity Purified

Description

Affinity Purified Nucleoside diphosphate kinase A Antibody

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 1-100 on human NDKA protein.

Accession #

GenBank: AAO85436.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P15531

Overview

Major role in the synthesis of nucleoside triphosphates other than ATP.

Molecular Function

Kinase, Transferase

Subcellular Location

Cytoplasm, Nucleus

Expression

heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen,thymus and lung carcinoma cell lines

Structure

Hexamer of two different chains: A and B

Alternative Nomenclature

AWD antibody

GAAD antibody

Granzyme A activated DNase antibody

Metastasis inhibition factor nm23 antibody

NB antibody

NDK A antibody

NM23 antibody

NME 1 antibody

Non metastatic cells 1 protein antibody

Nonmetastatic protein 23 antibody

Nucleoside diphosphate kinase A antibody

Tumor metastatic process associated protein antibody

General Information

Product

NME2 + NM23A Antibody

Description

Affinity Purified Nucleoside diphosphate kinase A and Nucleoside diphosphate kinase B Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 100-150 on NM23A protein selective for both NDKA and NDKB.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P15531

Overview

Major role in the synthesis of nucleoside triphosphates other than ATP.

Molecular Function

Kinase, Transferase

Subcellular Location

Cytoplasm, Nucleus

Expression

heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen,thymus and lung carcinoma cell lines

Structure

Hexamer of two different chains: A and B

Alternative Nomenclature

C myc purine binding transcription factor PUF antibody

Histidine protein kinase NDKB antibody

MGC111212 antibody

MGC2212 antibody

NDK B antibody

NM23B antibody

nme2 antibody

Nucleoside diphosphate kinase B antibody

PUF antibody

General Information

Product

nmt55 / NONO / p54nrb Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 430-471 on human NonO protein.

Accession #

GenBank: CAG33042.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q15233

Overview

DNA- and RNA binding protein, involved in several nuclear processes

Molecular Function

Activator, Repressor

Subcellular Location

Nucleus

Expression

Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Also found in a number of breast tumor cell lines.

Structure

Monomer and component of the SFPQ-NONO complex

Alternative Nomenclature

52 kDa subunit antibody

54 kDa nuclear RNA and DNA binding protein antibody

DNA-binding p52/p100 complex antibody

NMT 55 antibody

Non Pou domain containing octamer (ATGCAAAT) binding protein antibody

Nono antibody

NRB 54 antibody

P54 antibody

p54nrb antibody

General Information

Product

Npas4 Antibody Affinity Purified

Description

Affinity Purified NPAS4 protein Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on human Npas4 protein.

Accession #

GenBank: AAI43631.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1;10,000

ELISA

1;10,000

Western Blot

1:500

Protein

Uniprot #

Q8IUM7

Overview

Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene.

Molecular Function

DNA binding;signal transducer activity

Subcellular Location

Nucleus

Expression

Brain.

Alternative Nomenclature

bHLH PAS type transcription factor NXF antibody

bHLHe79 antibody

Class E basic helix-loop-helix protein 79 antibody

HLH-PAS transcription factor NXF antibody

Le PAS antibody

Neuronal PAS4 antibody

NXF antibody

PAS domain-containing protein 10 antibody

PASD10 antibody

General Information

Product

Pax2 Antibody

Description

Affinity Purified Paired box protein Pax-2 Antibody Multi-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50, 255-305, and 310-360 on human PAX2 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75-0.95 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Multi-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q02962

Overview

Probable transcription factor that may have a role in kidney cell differentiation. Has a critical role in the development of the urogenital tract, the eyes, and the CNS.

Molecular Function

Developmental protein, core promoter proximal region sequence-specific DNA binding, DNA binding

Subcellular Location

Nucleus

Expression

Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system.

Structure

Mainly in fetal kidney and juvenile nephrogenic rests.

Alternative Nomenclature

Paired box 2 antibody

Paired box gene 2 antibody

paired box protein 2 antibody

Paired box protein Pax 2 antibody

Pax 2 antibody

General Information

Product

Pax2 Antibody BIOTIN-Conjugated

Description

BIOTIN-Conjugated Pan Paired box protein Pax-2 Antibody Mid-region

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 255-305 on human PAX2 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75-0.95 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

BIOTIN-Conjugated

Clonality

Polyclonal

Determinant

Mid-region

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q02962

Overview

Probable transcription factor that may have a role in kidney cell differentiation. Has a critical role in the development of the urogenital tract, the eyes, and the CNS.

Molecular Function

Developmental protein, core promoter proximal region sequence-specific DNA binding, DNA binding

Subcellular Location

Nucleus

Expression

Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system.

Structure

Mainly in fetal kidney and juvenile nephrogenic rests.

Alternative Nomenclature

Paired box 2 antibody

Paired box gene 2 antibody

paired box protein 2 antibody

Paired box protein Pax 2 antibody

Pax 2 antibody

General Information

Product

Pax2 Antibody

Description

Affinity Purified Pan Paired box protein Pax-2 Antibody C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 310-360 on human PAX2 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75-0.95 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q02962

Overview

Probable transcription factor that may have a role in kidney cell differentiation. Has a critical role in the development of the urogenital tract, the eyes, and the CNS.

Molecular Function

Developmental protein, core promoter proximal region sequence-specific DNA binding, DNA binding

Subcellular Location

Nucleus

Expression

Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system.

Structure

Mainly in fetal kidney and juvenile nephrogenic rests.

Alternative Nomenclature

Paired box 2 antibody

Paired box gene 2 antibody

paired box protein 2 antibody

Paired box protein Pax 2 antibody

Pax 2 antibody