General Information

Product

ANGPTL5 Antibody

Description

Affinity Purified Angiopoietin-related protein 5 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 340-388 on human ANGPTL5 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.66 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q86XS5

Overview

Growth factors specific for vascular endothelium.  Modulate angiogenesis and maintain vascular integrity.

Molecular Function

Secreted; extracellular region

Expression

Mainly expressed in adult heart

Structure

Contains 1 fibrinogen C-terminal domain

Alternative Nomenclature

Fibrinogen like antibody

General Information

Product

Annexin A1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human annexin A1 protein.

Accession #

NCBI:  NP_000691

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P04083

Overview

Calcium/phospholipid-binding protein that promotes membrane fusion and is invovled in excocytosis.  Regulates phospholipase A2 activity.

Molecular Function

Phospholipase A2 inhibitor

Subcellular Location

Nucleus; Cytoplasm; Cell projection, cilium; Basolateral cell membrane

Expression

Detected in resting neutrophils. Detected in peripheral blood T-cells. Detected in extracellular vesicles in blood serum from patients with inflammatory bowel disease, but not in serum from healthy donors. Detected in placenta. Detected in liver.

Structure

Homodimer in placenta; linked by transgultamylation.

Alternative Nomenclature

ANX 1 antibody

ANX A1 antibody

Calpactin 2 antibody

Chromobindin 9 antibody

Lipocortin 1 antibody

LPC1 antibody

p35 antibody

Phospholipase A2 inhibitory protein antibody

General Information

Product

Annexin A10 Antibody

Description

Affinity Purified annexin A10 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Rat

Immunogen

Synthetic peptide taken within amino acid region 60-100 on human Annexin A10 protein.

Accession #

NCBI:  NP_009124

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DOT Blot

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9UJ72

Overview

Caclium-dependent phospholipid binding and calcium ion binding

Subcellular Location

Mitochondrion

Structure

Contains 4 annexin repeats; belongs to annexin family.

Alternative Nomenclature

annexin 14 antibody

ANX 14 antibody

ANXA 10 antibody

General Information

Product

Annexin A6 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 500-560 on human Annexin A6 protein.

Accession #

GenBank: AAH17046

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P08133

Overview

Regulates release of calcium ions from intracellular stores.  Associated with CD21

Molecular Function

Calcium and phospholipid-binding

Subcellular Location

Cytoplasm; Melanosome

Expression

Induced by Epstein-Barr virus

Structure

Pair of annexin repeats may form one binding site for calcium and phospholipid.  Contains 8 annexin repeats.

Alternative Nomenclature

67 kDa calelectrin antibody

ANX 6 antibody

Calcium binding protein p68 antibody

Calphobindin II antibody

CBP68 antibody

Chromobindin 20 antibody

p68 antibody

P70 antibody

Protein III antibody

General Information

Product

Annexin A9 Antibody

Description

Affinity Purified annexin A9 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-100 on human Annexin A9 protein.

Accession #

NCBI:  NP_003559

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Dot Blot

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

O76027

Overview

Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes.

Molecular Function

acetylcholine receptor activity; phospholipid binding; synaptic transmission; calcium ion binding

Subcellular Location

Cell surface; cytosol; extracellular vesicular exosome

Expression

Expressed in the stratified squamous skin epithelium, but not in epithelia of other types.

Structure

Homodimer

Alternative Nomenclature

annexin 31 antibody

ANX31 antibody

ANXA9 antibody

Pemphaxin antibody

General Information

Product

Aph 1b Antibody

Description

Affinity Purified Presenelin-stabiliziation factor-like Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

C. elegans, Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 235-257 of Human Presenilin stabilizing protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.6 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q8WW43

Overview

Subunit of gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and beta-amyloid precursor protein.

Molecular Function

Notch signaling pathway

Subcellular Location

Membrane; Multi-pass protein

Expression

Weakly expressed in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, thymus, colon, skeletal muscle, heart, and brain.

Structure

Component of gamma-secretase complex.  Interacts with PSEN1 and PSEN2.

Alternative Nomenclature

Anterior pharynx defective 1B like antibody

Gamma secretase subunit APH 1B antibody

Presenilin stabilisation factor like antibody

PRO1328 antibody

PSFL antibody

TAAV 688 antibody

General Information

Product

Aquaporin 1 Antibody

Verified Applications

ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Sheep, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 215-265 on human Aquaporin 1 protein.

Accession #

GenBank:  AAL87136

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.59 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P29972

Overview

Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

Molecular Function

Blood group antigen; Transport

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Detected in erythrocytes (at protein level). Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver.

Structure

Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).

Alternative Nomenclature

AQP 1 antibody

AQP CHIP antibody

aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group) antibody

Aquaporin CHIP antibody

Aquaporin-1 antibody

Channel forming integral protein 28kDa antibody

Channel like integral membrane protein 28 kDa antibody

CHIP 28 antibody

CO antibody

Colton blood group antibody

Growth factor induced delayed early response protein antibody

MGC26324 antibody

Urine water channel antibody

Water channel protein CHIP 29 antibody

Water channel protein for red blood cells and kidney proximal tubule antibody

General Information

Product

Aquaporin 10 Antibody

Verified Applications

ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-300 on human Aquaporin 10 protein.

Accession #

NCBI: XP_011508406.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.88 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

UPI0005D02B6D

Overview

Water cahnnel promoting glycerol permeability and water transport.  Contributes to water transport in upper portion of small intestine.

Molecular Function

Transport

Subcellular Location

Membrane; Multi-pass protein

Expression

Duodenum and jejunum.  Highest expression in absorptive epithelial cells at the tips of villi in the jejunum

Structure

Contain two tandem repeats each with three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala

Alternative Nomenclature

AQP 10 antibody

AQPA Human antibody

Aquaglyceroporin-10 antibody

Aquaporin-10 antibody

Small intestine aquaporin antibody

General Information

Product

Aquaporin 11 Antibody

Verified Applications

CM, ELISA, ICC/IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Pig, Rat

Immunogen

Synthetic peptide taken within amino acid region 140-190 on Aquaporin 11 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.57-0.67 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:50

Immunofluorescence

1:50

Immunohistochemistry

1:500

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q8CHM1

Overview

Transport of water and small neutral solutes across cell membranes

Molecular Function

Transport

Subcellular Location

Membrane; Multi-pass protein

Expression

Dendrite, cell surface, plasma membrane, endoplasmic reticulum

Structure

Contain two tandem repeats each with three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala

Alternative Nomenclature

AQP-11 antibody

Aquaporin-11 antibody

General Information

Product

Aquaporin 12 Antibody

Verified Applications

ELISA, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 240-290 on mouse Aquaporin 12 protein.

Accession #

GenBank:  EDL39975

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61-0.67 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q3V2I1

Overview

Water transport activity

Molecular Function

Transport

Subcellular Location

Membrane

Expression

Cytoplasm; plasma membrane; integral component of membrane

Structure

Contain two tandem repeats each with three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala

Alternative Nomenclature

AQP 12 antibody

AQP 12A antibody

AQPX2 antibody

Aquaporin 12 antibody

Aquaporin 12A antibody

Aquaporin X2 antibody