General Information

Product

Aquaporin 9 Antibody

Verified Applications

ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Sheep, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-294 on rat Aquaporin 9 protein.

Accession #

NCBI:  NP_075249

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.8 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P56627

Overview

Forms a channel with broad specificity.  Mediates passage of wide variety of non-charged solutes.

Molecular Function

Transport

Expression

Highly expressed in peripheral leukocytes. Also expressed in liver, lung, and spleen.

Subcellular Location

Membrane; Multi-pass protein

Structure

Contain two tandem repeats each with three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala

Alternative Nomenclature

AQP 9 antibody

Aquaglyceroporin-9 antibody

Aquaporin 9 antibody

HsT 17287 antibody

Small solute channel 1 antibody

SSC 1 antibody

General Information

Product

Aquaporin 11 Antibody

Verified Applications

CM, ELISA, ICC/IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Pig, Rat

Immunogen

Synthetic peptide taken within amino acid region 140-190 on Aquaporin 11 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.57-0.67 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:50

Immunofluorescence

1:50

Immunohistochemistry

1:500

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q8CHM1

Overview

Transport of water and small neutral solutes across cell membranes

Molecular Function

Transport

Subcellular Location

Membrane; Multi-pass protein

Expression

Dendrite, cell surface, plasma membrane, endoplasmic reticulum

Structure

Contain two tandem repeats each with three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala

Alternative Nomenclature

AQP-11 antibody

Aquaporin-11 antibody

General Information

Product

Aquaporin 10 Antibody

Verified Applications

ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-300 on human Aquaporin 10 protein.

Accession #

NCBI: XP_011508406.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.88 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

UPI0005D02B6D

Overview

Water cahnnel promoting glycerol permeability and water transport.  Contributes to water transport in upper portion of small intestine.

Molecular Function

Transport

Subcellular Location

Membrane; Multi-pass protein

Expression

Duodenum and jejunum.  Highest expression in absorptive epithelial cells at the tips of villi in the jejunum

Structure

Contain two tandem repeats each with three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala

Alternative Nomenclature

AQP 10 antibody

AQPA Human antibody

Aquaglyceroporin-10 antibody

Aquaporin-10 antibody

Small intestine aquaporin antibody

General Information

Product

Glucose Transporter GLUT7 Antibody 

Description

Affinity Purified Solute carrier family 2, facilitated glucose transporter member 7 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on rat GLUT7 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,500

ELISA

1:4,500

Immunoprecipitation

1:200

Western Blot

1:500-1:750

Protein

Overview

High-affinity transporter for glucose and fructose Does not transport galactose, 2-deoxy-d-glucose and xylose.

Molecular Function

substrate-specific transmembrane transporter activity

Subcellular Location

Membrane; Multi-pass membrane protein

Expression

Expressed in small intestine and colon. Weakly expressed in testis and prostate.

Alternative Nomenclature

facilitated glucose transporter member 7 antibody

Glucose transporter type 7 antibody

GLUT7 antibody

Intestinal facilitative glucose transporter 7 antibody

RP5-963K15.3 antibody

SLC2A7 antibody

Solute carrier family 2 (facilitated glucose transporter), member 7 antibody

Solute carrier family 2 antibody

General Information

Product

SLC12A1 Antibody Affinity Purified

Description

Affinity Purified NKCC2 variant A Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 30-60 on NKCC2 protein.

Accession #

GenBank: ABU63482.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

A8JYG7

Molecular Function

cation:chloride symporter activity

Subcellular Location

integral component of membrane

Alternative Nomenclature

BSC1 antibody

Bumetanide sensitive sodium 3 antibody

Kidney-specific Na-K-Cl symporter antibody

MGC48843 antibody

NKCC2 antibody

potassiumchloride cotransporter 2 antibody

Slc12a1 antibody

sodium potassium chloride cotransporter 2 antibody

solute carrier family 12

General Information

Product

CCR3 Antibody

Description

Affinity Purified C-C chemokine receptor type 3 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human CCR3 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.60-0.70 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P51677

Overview

Receptor for C-C type chemokine.  Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta.

Molecular Function

C-C receptor activity; Host-virus interaction; Receptor; Transducer

Subcellular Location

Cell membrane; Mulipass membrane protein.

Expression

eosinophils and trace amounts in neutrophils and monocytes

Structure

Binds to HIV-1 Tat.

Alternative Nomenclature

B Chemokine Receptor antibody

CC CKR 3 antibody

CD 193 antibody

CMKBR 3 antibody

CMKBR1L2 antibody

Eosinophil CC Chemokine Receptor 3 antibody

Eosinophil Eotaxin Receptor antibody

Macrophage inflammatory protein 1 alpha receptor like 2 antibody

MIP1 Alpha RL2 antibody

General Information

Product

GGCX Antibody 

Description

Affinity Purified Gamma-glutamic carboxylase Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 400-450 on human GGCX protein.

Accession #

GenBank: AAA91834.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DOT Blot

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P38435

Overview

Mediates the vitamin K-dependent carboxylation of glutatmate residues to calcium-binding gamma-carboxyglutamate residues with the concomitant converstion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.

Molecular Function

gamma-glutamyl carboxylase activity; Lyase

Subcellular Location

Endoplasmic Reticulum membrane; Multi-pass membrane protein

Expression

Monomer; may interact with CALU

Alternative Nomenclature

FLJ26629 antibody

Gamma glutamyl carboxylase antibody

Gamma-glutamyl carboxylase antibody

GC antibody

GGCX antibody

Peptidyl glutamate 4 carboxylase antibody

Peptidyl-glutamate 4-carboxylase antibody

Vitamin K dependent gamma carboxylase antibody

Vitamin K gamma glutamyl carboxylase antibody

Vitamin K-dependent gamma-carboxylase antibody

VKCFD 1 antibody

VKCFD1 antibody

VKGC_HUMAN antibody

General Information

Product

Glucose Transporter GLUT1 Antibody

Description

Glucose transporter glycoprotein GLUT1 Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Sheep

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequences on GLUT1 protein.

Accession #

GenBank: AAC28635.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:12,000

ELISA

1:12,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:5,000

Protein

Uniprot #

P11166

Overview

Facilitative glucose transporter. May be responsible for constitutive or basal glucose uptake.

Molecular Function

Sugar Transport

Subcellular Location

Cell membrane; Multi-pass membrane protein; melanosome

Expression

Detected in erythrocytes. Variable expression in many human tissues.

Structure

Transmembrane helix

Alternative Nomenclature

DYT17 antibody

DYT18 antibody

erythrocyte/brain antibody

Erythrocyte/hepatoma glucose transporter antibody

facilitated glucose transporter member 1 antibody

Glucose transporter type 1 erythrocyte/brain antibody

GLUT1DS antibody

GLUTB antibody

GT1 antibody

GTG1 antibody

Gtg3 antibody

HepG2 glucose transporter antibody

MGC141895 antibody

MGC141896 antibody

PED antibody

RATGTG1 antibody

SLC2A1 antibody

Solute carrier family 2, facilitated glucose transporter member 1 antibody

General Information

Product

Annexin A1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human annexin A1 protein.

Accession #

NCBI:  NP_000691

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P04083

Overview

Calcium/phospholipid-binding protein that promotes membrane fusion and is invovled in excocytosis.  Regulates phospholipase A2 activity.

Molecular Function

Phospholipase A2 inhibitor

Subcellular Location

Nucleus; Cytoplasm; Cell projection, cilium; Basolateral cell membrane

Expression

Detected in resting neutrophils. Detected in peripheral blood T-cells. Detected in extracellular vesicles in blood serum from patients with inflammatory bowel disease, but not in serum from healthy donors. Detected in placenta. Detected in liver.

Structure

Homodimer in placenta; linked by transgultamylation.

Alternative Nomenclature

ANX 1 antibody

ANX A1 antibody

Calpactin 2 antibody

Chromobindin 9 antibody

Lipocortin 1 antibody

LPC1 antibody

p35 antibody

Phospholipase A2 inhibitory protein antibody

General Information

Product

Phospho-BTK Antibody (Y551)

Description

Affinity Purified Phospho-specific Bruton's Tyrosine Kinase Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Pig, Rat

Immunogen

Synthetic peptide corresponding to Human BTK amino acids 544-561 (phopsho Y551). 

Sequence 

RYV LDD EY(p)T SSV GSK FPV

Accession #

NCBI:  NP_000052.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.6 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500. Predicted molecular weight: 76 kDa.

Protein

Uniprot #

Q06187

Overview

Non-receptor tyrosine kinase invovled in B lymphocyte development.

Molecular Function

Kinase; Transferase; Tyrosine-protein Kinase

Subcellular Location

Cytoplasm; Cell Membrane; Peripheral membrane: Nucleus.  In steady state BTK is predominantly cytosolic.

Expression

B-lymphocytes

Structure

PH domain mediates binding to inositol polyphosphate and phosphoinositides, leading to its targeting with plasma membrane.  Extended in the BTK kinase family by a region designated Tec homology domain, which has roughly 80 residues preceding SH3 domain.

Alternative Nomenclature

Agammaglobulinaemia tyrosine kinase antibody

AGMX 1 antibody

AT antibody

ATK antibody

B cell progenitor kinase antibody

BPK antibody

Bruton tyrosine kinase antibody

Btk antibody

IMD1 antibody

MGC126261 antibody

MGC126262 antibody

PSCTK 1 antibody

Tyrosine protein kinase BTK antibody

XLA antibody