General Information

Product

SESN2 Antibody

Description

Affinity Purified Sestrin 2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-80 on SESN2 protein.

Accession #

GenBank: AAM92261.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P58004

Overview

Involved in the reduction of peroxiredoxins.

Subcellular Location

Cytoplasm, Nucleus

Expression

Widely expressed.

Alternative Nomenclature

Hi95 antibody

Hypoxia induced gene 95 antibody

RP23 63D8.3 antibody

SES2 antibody

SEST2 antibody

General Information

Product

SESN3 Antibody Affinity Purified

Description

Affinity Purified SESN3 protein Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on SESN3 protein.

Accession #

GenBank: AAH17296.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68-0.80 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P58005

Subcellular Location

Nucleus

Expression

Widely expressed.

Alternative Nomenclature

SEST3 antibody
Sestrin 3 antibody

General Information

Product

UCN2 Antibody Affinity Purified

Description

Affinity Purified Urocortin-2 preprotein Antibody

Verified Applications

ELISA, SB, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken wtihin amino acid region 70-115 of human Urocortin 2 protein.

Accession #

NCBI:  NP_149976.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.71 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q96RP3

Overview

Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

Molecular Function

Hormone binding, receptor binding, hormone

Subcellular Location

Secreted

Expression

Binds with high affinity to CRF receptors 2-alpha and 2-beta.

Alternative Nomenclature

SRP

Stresscopin-related peptide

Ucn II

UCN2

UCNI

UR

Urocortin II

Urocortin-2

Urocortin-related peptide

URP

General Information

Product

HIF-1-Alpha isoform 1 Antibody

Description

Affinity Purified Hypoxia-inducible factor 1-alpha isoform 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 790-826 on human HIF1A protein.

Accession #

NCBI:  NP_001521.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.57 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q16665

Overview

Functions as a master transcriptional regulator of the adaptive response to hypoxia.

Molecular Function

Activator

Subcellular Location

Cytoplasm, Nucleus

Expression

highest levels in kidney and heart;common human cancers and their metastases, due to the presence of intratumoral hypoxia

Structure

Heterodimer

Alternative Nomenclature

ARNT interacting protein antibody

Basic-helix-loop-helix-PAS protein MOP1 antibody

bHLHe78 antibody

Class E basic helix-loop-helix protein 78 antibody

HIF 1A antibody

HIF 1alpha antibody

Hypoxia inducible factor 1 alpha antibody

Member of PAS protein 1 antibody

Member of PAS superfamily 1 antibody

MOP1 antibody

PAS domain-containing protein 8 antibody

PASD8 antibody

General Information

Product

Smad1 Antibody Affinity Purified

Description

Affinity Purified Mothers against dpp Antibody

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Drosophila melanogaster

Immunogen

Synthetic peptide taken within amino acid region 405-455 on D. melanogaster Mothers against dpp protein.

Accession #

NCBI:  NP_477017.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.0 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P42003

Overview

Required for the function of decapentaplegic. May play an important role in mediating Dpp signaling. Involved in the BMP signaling pathway.

Molecular Function

DNA binding; RNA polymerase II activating transcription factor; Transcription regulatory region sequence-specific activity; Transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity

Subcellular Location

Cytoplasm; Nucleus

Expression

Is detected in all developmental stages, though it appears most abundant in pupae, adult stages and early embryos. Its abundance decreases throughout embryonic and larval development and then returns to high levels in pupae and adult females.

Structure

Homotrimer

Alternative Nomenclature

BSP 1 antibody

Dwarfin A antibody

DwfA antibody

JV 41 antibody

MAD homolog 1 antibody

MAD mothers against decapentaplegic homolog 1 antibody

Mad related protein 1 antibody

MADR1 antibody

Mothers against DPP homolog 1 antibody

Sma and Mad related protein 1 antibody

SMAD 1 antibody

Spinal muscular atrophy distal with upper limb predominance antibody

TGF beta signaling protein 1 antibody

Transforming growth factor beta signaling protein 1 antibody

General Information

Product

Phospho-alpha Actinin 4 (S159) antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic phospho-peptide, corresponding to a region within amino acid regions 140-190 of Human alpha Actinin 4 conjugated to a carrier protein.

Accession #

NCBI:  NP_004915

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.62 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500 Predicted molecular weight: 105kDa

Protein

Uniprot #

O43707

Overview

F-actin cross-linking protein that anchors variety of intracellular structures.  Bundling protein involved in vesicular trafficking via its association with the CART complex.

Molecular Function

Protein Transport; Actin-binding

Subcellular Location

Cytoplasmic mRNP granules containing untranslated mRNAs.  Colocalizes with actin stress fibers.

Expression

Induced by pI3 kinase inhibitor wortmannin or by cytochalasin D.  Localized in the nucleus.

Structure

Widely Expressed

Alternative Nomenclature

actinin 4 antibody

Actinin alpha 4 antibody

ACTN 4 antibody

DKFZp686K23158 antibody

F actin cross linking protein antibody

Focal segmental glomerulosclerosis 1 antibody

FSGS 1 antibody

General Information

Product

SOCS3 Antibody

Description

Affinity Purified Suppresor of Cytokine Signaling 3 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 175-225 on human SOCS3 protein.

Accession #

GenBank:  CAG46495

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q6FI39

Molecular Function

Protein modification; protein ubiquitination.

Subcellular Location

Cytoplasm

Expression

Widely expressed with high expression in heart, placenta, skeletal muscle, peripheral blood leukocytes, fetal and adult lung, and fetal liver and kidney. Lower levels in thymus.

Alternative Nomenclature

ATOD4 antibody

CIS 3 antibody

Cish3 antibody

Cytokine induced SH2 protein 3 antibody

E2a Pbx1 target gene in fibroblasts 10 antibody

EF 10 antibody

SOCS 3 antibody

SSI3 antibody

STAT induced STAT inhibitor 3 antibody

Suppressor of cytokine signaling 3 antibody

General Information

Product

TTC27 Antibody Affinity Purified

Description

Affinity Purified Tetratricopeptide repeat protein 27 Antibody

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Zebra Fish

Immunogen

Synthetic peptide taken within amino acid region 100-150 on Tetratricopeptide repeat protein 27 Danio rerio protein.

Accession #

NCBI:  NP_775392.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q8CD92

Structure

Belongs to the TTC27 family.  Contains 6 TPR repeats.

Alternative Nomenclature

FLJ20272 Antibody

Tetratricopeptide repeat domain 27 Antibody

TPR repeat protein 27 Antibody

TTC27 Antibody

General Information

Product

LCT Antibody

Description

Affinity Purified Lactase Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1080-1130 on rat Lactase protein.

Accession #

GenBank:  EDM09876.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.87 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:50

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:50

Immunofluorescence

1:50

Immunohistochemistry

1:50

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

UPI000154E3A5

Overview

LPH splits lactose in the small intestine.

Molecular Function

Glycosylceramidase activity; lactase activity

Subcellular Location

Apical cell membrane; Single-pass type I membrane protein

Expression

Intestine

Structure

The sequence exhibits 4 regions (I-IV) of internal homology; therefore LPH might have evolved by two cycles of partial gene duplication.

Alternative Nomenclature

LAC antibody

Lactase antibody

Lactase phlorizin hydrolase 1 antibody

Lactase-glycosylceramidase antibody

Lct antibody

LPH antibody

LPH1 antibody

Phlorizin hydrolase antibody

General Information

Product

Nicotinic Acetylcholine Receptor alpha 7 Antibody

Description

Affinity Purified Neuronal acetylcholine receptor subunit alpha-7 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Rat

Immunogen

Synthetic peptide corresponding to exon 5 of alpha 7-2 nAChRs protein.

Accession #

GenBank: XP_008757720

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75-0.95 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:250

Protein

Uniprot #

Q05941

Overview

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.

Molecular Function

Ion channel, Ligand-gated ion channel, Receptor

Subcellular Location

Cell junction › synapse › postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein

Structure

Homopentamer. Interacts with RIC3; which is required for proper folding and assembly.

Alternative Nomenclature

7nAChR antibody

A7 nicotinic acetylcholine receptor antibody

alpha-7 subunit antibody

AChR antibody

Acra7 antibody

Alpha 7 neuronal nicotinic acetylcholine receptor antibody

Alpha7 antibody

Alpha7 nicotinic receptor antibody

Cholinergic receptor nicotinic alpha 7 antibody

CHRNA7 antibody

CHRNA7-2 antibody

NACHRA 7 antibody

Neuronal acetylcholine receptor protein alpha 7 chain precursor antibody

Nicotinic acetylcholine alpha 7 subunit antibody

Schizophrenia neurophysiologic defect candidate antibody