General Information

Product

PrLZ / TPD52 Antibody

Description

Affinity Purified Prostate leucine zipper isoform 5 Antibody N-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human Prostate leucine zipper isoform 5 protein.

Accession #

NCBI:  NP_001020423.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.69 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DOT Blot

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Western Blot

1:500-1:1,000

Protein

Uniprot #

P55327

Molecular Function

calcium ion binding, protein heterodimerization activity, protein homodimerization activity

Subcellular Location

cytoplasm, perinuclear region of cytoplasm, endoplasmic reticulum

Expression

Isoform 2 is expressed in colon, breast, prostate, pancreas and kidney tumor cell lines. Isoform 2 is expressed at high levels in kidney, prostate, brain, small intestine and pancreas, at moderate levels in placenta and colon, at low levels in lung, liver and heart, and at very low levels in spleen, thymus, peripheral mononuclear blood cells, testis and ovary. 

Structure

Forms a homodimer or heterodimer with other members of the family. All isoforms interact with several 14-3-3 proteins.

Alternative Nomenclature

D52 antibody

Human 19.8 kDa protein mRNA, complete cds antibody

N8L antibody

PC 1 antibody

PC1/MRPS28 fusion protein antibody

PrLZ antibody

Prostate and colon associated protein antibody

Prostate leucine zipper antibody

Protein N8 antibody

TPD52 antibody

Tumor protein D52 antibody

1:150

General Information

Product

LYK5 Antibody

Description

Affinity Purified STE20-related kinase adapter protein alpha Antibody C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 381-431 on human STE-20 related kinase adapter protein alpha.

Accession #

NCBI:  NP_001003787.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q7RTN6

Overview

Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

Molecular Function

ATP Binding, protein kinase activator activity, kinase binding, transferase activity, transferring phosphorus-containing groups

Subcellular Location

Nucleus, cytoplasm

Expression

Expressed in liver

Structure

Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

Contains 1 protein kinase domain.

Alternative Nomenclature

Protein kinase LYK5 antibody

Serologically defined breast cancer antigen NY BR 96 antibody

STE20 related adapter protein antibody

STRAD alpha antibody

STRAD antibody

General Information

Product

LYK5 Antibody

Description

Affinity Purified STE20-related kinase adapter protein alpha Antibody N-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 50-100 on human STE-20 related kinase adapter protein alpha.

Accession #

NCBI:  NP_001003787.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q7RTN6

Overview

Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

Molecular Function

ATP Binding, protein kinase activator activity, kinase binding, transferase activity, transferring phosphorus-containing groups

Subcellular Location

Nucleus, cytoplasm

Expression

Expressed in liver

Structure

Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

Contains 1 protein kinase domain.

Alternative Nomenclature

Protein kinase LYK5 antibody

Serologically defined breast cancer antigen NY BR 96 antibody

STE20 related adapter protein antibody

STRAD alpha antibody

STRAD antibody

General Information

Product

KK-LC-1 Antibody

Description

Affinity Purified Kita-kyushu lung cancer antigen 1 Antibody N-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 20-70 on human Kita-kyushu lung cancer antigen 1.

Accession #

NCBI:  NP_001017978

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.6 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q5H943

Subcellular Location

Cell membrane; Single-pass type II membrane protein

Expression

Specifically expressed in testis. Expressed by cancer cell lines.

Alternative Nomenclature

Cancer/testis antigen 83 antibody

Chromosome X open reading frame 61 antibody

CT83 antibody

CXorf61 antibody

Kita-kyushu lung cancer antigen 1 antibody

KKLC1 antibody

General Information

Product

KK-LC-1 Antibody

Description

Affinity Purified Kita-kyushu lung cancer antigen 1 Antibody C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 61-111 on human Kita-kyushu lung cancer antigen 1.

Accession #

NCBI:  NP_001017978

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.6 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q5H943

Subcellular Location

Cell membrane; Single-pass type II membrane protein

Expression

Specifically expressed in testis. Expressed by cancer cell lines.

Alternative Nomenclature

Cancer/testis antigen 83 antibody

Chromosome X open reading frame 61 antibody

CT83 antibody

CXorf61 antibody

Kita-kyushu lung cancer antigen 1 antibody

KK-LC-1 antibody

KKLC1 antibody

General Information

Product

ZDHHC9 Antibody

Description

Affinity Purified Palmitoyltransferase ZDHHC9 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-300 on human Palmitoyltransferase ZDHHC9 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9Y397

Overview

The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS.

Molecular Function

Acyltransferase, Transferase

Subcellular Location

Endoplasmic reticulum membrane; Golgi apparatus membrane

Expression

Highly expressed in kidney, skeletal muscle, brain, lung and liver. Absent in thymus, spleen and leukocytes.

Structure

Interacts with GOLGA7.

Alternative Nomenclature

Antigen MMSA 1 antibody

Asp His His Cys domain containing protein 9 antibody

CGI89 antibody

CXorf11 antibody

DHHC9 antibody

MMSA1 antibody

MRXSZ antibody

Palmitoyltransferase ZDHHC9 antibody

ZDHHC 9 antibody

ZDHHC10 antibody

Zinc finger DHHC domain containing 10 antibody

Zinc finger DHHC domain containing protein 9 antibody

Zinc finger DHHC type containing 9 antibody

Zinc finger protein 379 antibody

Zinc finger protein 380 antibody

ZNF379 antibody

ZNF380 antibody

General Information

Product

ALDH1A1 Antibody

Description

Affinity Purified Aldehyde Dehydrogenase family 1 member A1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 441-491 on rat retinal dehydrogenase 1 protein.

Accession #

NCBI:  NP_071852

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

P51647

Overview

Is capable of converting 9-cis and all-trans retinal to corresponding retinoic acid with high efficiency, 9-cis retinal being 2-fold more active than all-trans retinal.

Molecular Function

Oxidoreductase

Subcellular Location

Cytoplasm

Expression

Strongly expressed in kidney, lung, testis, intestine, stomach, and trachea, but weakly in the liver.

Structure

Belongs to the aldehyde dehydrogenase family.

Alternative Nomenclature

Acetaldehyde dehydrogenase 1 antibody

AHD2 antibody

ALDC antibody

Aldehyde dehydrogenase 1 family member A1 antibody

Aldehyde dehydrogenase 1 soluble antibody

Aldehyde dehydrogenase 1A1 antibody

Aldehyde dehydrogenase antibody

Aldehyde dehydrogenase cytosolic antibody

Aldehyde dehydrogenase liver cytosolic antibody

ALDH 1 antibody

ALDH 1A1 antibody

ALDH class 1 antibody

ALDH, liver cytosolic antibody

ALDH-E1 antibody

ALDH1 antibody

ALDH11 antibody

ALDH1A1 antibody

ALHDII antibody

epididymis luminal protein 12 antibody

epididymis luminal protein 9 antibody

epididymis secretory sperm binding protein Li 53e antibody

HEL-S-53e antibody

MGC2318 antibody

PUMB1 antibody

RALDH 1 antibody

Retinal dehydrogenase 1 antibody

General Information

Product

Bcl-XL Antibody

Description

Affinity Purified Bcl-2-like protein 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 150-200 on human BCL-2-like protein 1.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q07817

Overview

Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F1F0 activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles. May attenuate inflammation impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release. Isoform Bcl-X(S) promotes apoptosis.

Molecular Function

BH3 domain binding; Identical protein binding; Protein heterodimerization and homodimerization activity; protein kinase binding

Subcellular Location

Mitochondrion inner membrane

Mitochondrion outer membrane

Mitochondrion matrix

Cytoplasmic vesicle › secretory vesicle › synaptic vesicle membrane

Cytoplasm › cytosol

Cytoplasm › cytoskeleton › microtubule organizing center › centrosome

Nucleus membrane ; Single-pass membrane protein ; Cytoplasmic side

Note: After neuronal stimulation, translocates from cytosol to synaptic vesicle and mitochondrion membrane in a calmodulin-dependent manner. Localizes to the centrosome when phosphorylated at Ser-49.

Expression

Bcl-X(S) is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. In contrast, Bcl-X(L) is found in tissues containing long-lived postmitotic cells, such as adult brain.

Structure

The BH4 motif is required for anti-apoptotic activity. The BH1 and BH2 motifs are required for both heterodimerization with other Bcl-2 family members and for repression of cell death. The loop between motifs BH4 and BH3 is required for the interaction with NLRP1.

Alternative Nomenclature

Apoptosis regulator Bcl X antibody

B cell lymphoma 2 like antibody

B2CL1_HUMAN antibody

Bcl 2 like 1 protein antibody

Bcl X antibody

Bcl xL antibody

BCL XL/S antibody

Bcl xS antibody

Bcl-2-like protein 1 antibody

Bcl2 Like 1 antibody

Bcl2 related gene antibody

BCL2L antibody

BCLX antibody

PPP1R52 antibody

Protein phosphatase 1 regulatory subunit 52 antibody

General Information

Product

KK-LC-1 Antibody

Description

Affinity Purified Kita-kyushu lung cancer antigen 1 Antibody Multi-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 20-70 and 61-111 on human Kita-kyushu lung cancer antigen 1.

Accession #

NCBI:  NP_001017978

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.6 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Multiple epitopes

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q5H943

Subcellular Location

Cell membrane; Single-pass type II membrane protein

Expression

Specifically expressed in testis. Expressed by cancer cell lines.

Alternative Nomenclature

Cancer/testis antigen 83 antibody

Chromosome X open reading frame 61 antibody

CT83 antibody

CXorf61 antibody

Kita-kyushu lung cancer antigen 1 antibody

KK-LC-1 antibody

KKLC1 antibody

General Information

Product

KMT6 / EZH2 Antibody

Description

Affinity Purified Histone-lysine N-methyltransferase EZH2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 60-110 on human Histone-lysine N-methyltransferase EZH protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

A0A090N8E9

Molecular Function

chromatin DNA binding

histone-lysine N-methyltransferase activity

primary miRNA binding

ribonucleoprotein complex binding

RNA polymerase II core promoter sequence-specific DNA binding

RNA polymerase II proximal promoter sequence-specific DNA binding

Subcellular Location

Nucleus, Cytoplasm

Alternative Nomenclature

Enhancer of zeste 2 antibody

enhancer of zeste 2 polycomb repressive complex 2 subunit antibody

ENX 1 antibody

Enx1h antibody

EZH 2 antibody

EZH1 antibody

EZH2b antibody

Histone-lysine N-methyltransferase EZH2 antibody

KMT 6 antibody

KMT6A antibody

Lysine N-methyltransferase 6 antibody

WVS antibody

WVS2 antibody