General Information

Product

SUR1 Antibody

Description

Affinity Purified ATP-binding cassette sub-family C member 8 Antibody

Verified Applications

ELISA, IHC-Fr, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to positions 1560-1582.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.6 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000-1:100,000

ELISA

1:10,000-1:100,000

Western Blot

1:500

Protein

Uniprot #

Q09429

Overview

Putative subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K+ channels and insulin release.

Molecular Function

Receptor, ATPase activity, coupled to transmembrane movement of substances, ATP binding

Subcellular Location

Membrane; Multi-pass membrane protein

Structure

Interacts with KCNJ11.

Alternative Nomenclature

ABC36 antibody

Abcc8 antibody

ATP binding cassette sub family C (CFTR/MRP) member 8 antibody

HHF1 antibody

HI antibody

HRINS antibody

MRP8 antibody

PHHI antibody

Sulfonylurea receptor (hyperinsulinemia) antibody

SUR antibody

SUR1 antibody

SUR1delta2 antibody

TNDM2 antibody

General Information

Product

TORC2 Antibody

Description

Affinity Purified CREB-regulated transcription coactivator 2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse

Immunogen

Synthetic peptide taken within amino acid region 640-693 on human CREB-regulated transcription coactivator 2 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q53ET0

Overview

Activator, cAMP response element binding protein binding

Subcellular Location

Cytoplasm, Nucleus

Expression

Most abundantly expressed in the thymus. Present in both B and T-lymphocytes. Highly expressed in HEK293T cells and in insulinomas. High levels also in spleen, ovary, muscle and lung, with highest levels in muscle.

Alternative Nomenclature

CREB regulated transcription coactivator 2 antibody

CRTC2 antibody

TORC-2 antibody

Transducer of CREB protein 2 antibody

Transducer of regulated cAMP response element-binding protein antibody

Immunoprecipitation

General Information

Product

TRPV6 Antibody

Description

Affinity Purified Transient receptor potential cation channel, subfamily V, member 6 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken from the region within amino acids 700-732 of TRPV6 protein. The peptide was covalently modified to acheive desired antigenicity. Modified peptide was covalently coupled to a carrier protein by heterobifunctional cross linker for immunogen preparation.

Accession #

GenBank: EAW51899.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.67 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

UPI00000380EC

Overview

Calcium selective cation channel probably involved in Ca2+ uptake in various tissues, including Ca2+ reabsorption in intestine. The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both, a rapid Ca2+-dependent and a slower Ca2+-calmodulin-dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg2+ in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.

Molecular Function

Calcium channel activity; Calmodulin binding

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Abundantly expressed in pancreas and placenta, and to a much lesser extend in stomach and kidney. Not detected in intestine.

Structure

Homotetramer and probably heterotetramer with TRPV5. Interacts with TRPV5. Interacts with S100A10 and probably with the ANAX2-S100A10 heterotetramer. The interaction with S100A10 is required for the trafficking to the plasma membrane. Interacts with calmo

Alternative Nomenclature

ABPZF antibody

Alu binding protein with zinc finger domain antibody

Calcium channel CaT1 antibody

Calcium transport protein 1 antibody

CaT L antibody

CaT1 antibody

ecac antibody

ECaC2 antibody

Epithelial apical membrane calcium transporter/channel CaT1 antibody

Epithelial calcium channel 2 antibody

HSA277909 antibody

LP6728 antibody

NUDC antibody

Transient receptor potential cation channel subfamily V member 6 antibody

TrpV6 antibody

ZFAB antibody

General Information

Product

CAB13 Antibody

Description

Affinity Purified Chlorophyll a-b binding protein 13 Antibody

Verified Applications

DB, ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Plant

Immunogen

Synthetic peptide taken within amino acid region 100-200 on Solanum lycopersicum Chlorophyll a-b binding protein 13.

Physical Properties

Quantity

100 µg

Volume

200 µl

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Preservative: 0.02% Sodium azide
Constituents: 30% Glycerol, 69% Tris glycine

pH 7.4-7.8.Contains .5% stabilizing proteins.

Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P27489

Overview

Light receptor captures and delivers excitation energy to photosystems.

Molecular Function

Chlorophyll; Chromophore; Magnesium; Metal-binding

Subcellular Location

Chloroplast; Membrane; Photosystem I & II, Plastid; Thylakoid

Structure

N-terminus of the protein extends into the stroma where it is invovled with adhesion of granal membranes and post-translational modifications.

Alternative Nomenclature

Recombinant Solanum lycopersicum

Chloroplast (CAB13) Antibody

LHCII type III CAB-13 Antibody

General Information

Product

PDE11A Antibody

Description

Affinity Purified Cyclic Nucleotide Phosphodiesterase 11A1 Antibody N-epitope

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 100-150 on PDE11A protein, common to all PDE11A variants.

Accession #

GenBank: CAB82573.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Immunoprecipitation

1:250

Western Blot

1:500

Protein

Uniprot #

Q9HCR9

Overview

Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively.

Molecular Function

Hydrolase, metal-ion binding, cGMP binding

Subcellular Location

Cytoplasm

Expression

Isoform 1 is present in prostate, pituitary, heart and liver. It is however not present in testis nor in penis, suggesting that weak inhibition by Tadalafil is not relevant (at protein level). Isoform 2 may be expressed in testis. Isoform 4 is expressed i

Alternative Nomenclature

5''-cyclic-AMP and -GMP phosphodiesterase 11A antibody

cAMP and cGMP cyclic nucleotide phosphodiesterase 11A antibody

Cyclic nucleotide phosphodiesterase 11A1 antibody

Dual 3' 5' cyclic AMP and GMP phosphodiesterase 11A antibody

FLJ23693 antibody

MGC133355 antibody

MGC133356 antibody

PDE 11A antibody

pde11 antibody

pde11a2 antibody

Phosphodiesterase 11A antibody

PPNAD2 antibody

General Information

Product

PDE11A Antibody

Description

Affinity Purified Cyclic Nucleotide Phosphodiesterase 11A1 Antibody C-epitope

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide conjugated to KLH, corresponding to C terminal amino acids 454-468 of human PDE11A.

Accession #

GenBank: CAB82573.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Immunoprecipitation

1:250

Western Blot

1:500

Protein

Uniprot #

Q9HCR9

Overview

Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively.

Molecular Function

Hydrolase, metal-ion binding, cGMP binding

Subcellular Location

Cytoplasm

Expression

Isoform 1 is present in prostate, pituitary, heart and liver. It is however not present in testis nor in penis, suggesting that weak inhibition by Tadalafil is not relevant (at protein level). Isoform 2 may be expressed in testis.

Alternative Nomenclature

5''-cyclic-AMP and -GMP phosphodiesterase 11A 

cAMP and cGMP cyclic nucleotide phosphodiesterase 11A 

Cyclic nucleotide phosphodiesterase 11A1 

Dual 3' 5' cyclic AMP and GMP phosphodiesterase 11A 

PDE 11A 

pde11 

pde11a2 

Phosphodiesterase 11A 

PPNAD2 

General Information

Product

Stra6 Antibody

Description

Affinity Purified Retinoic acid-responsive protein Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within third large intra cytoplasmic loop within amino acid region 450-500 on human Stra6 protein.

Accession #

GenBank: BAB14122.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.69 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

O70491

Overview

May act as a high-affinity cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Acts by removing retinol from RBP/RBP4 and transports it across the plasma membrane, where it can be metabolized. This mechanism does not depend on endocytosis. Binds to RBP/RBP4 with high affinity.

Molecular Function

Receptor, Receptor activity

Subcellular Location

Cell membarane; Multi-pass membrane protein

Expression

Widely expressed in the embryo. In the adult, is highly expressed in cells that compose blood-organ barriers in the brain (choroid plexus and the brain microvascular), in the eye (retinal pigment epithelium), in testis (the basal layer of the seminiferous epithelium), in the yolk sac, and in the chorioallantoic placenta (at protein level). Also detected in kidney, spleen, and female genital tract; and at lower levels in heart and lung.

Alternative Nomenclature

MCOPCB8 antibody

MCOPS9 antibody

PP14296 antibody

Stimulated by retinoic acid 6 homolog antibody

Stimulated by retinoic acid gene 6 protein homolog antibody

STRA6 antibody

General Information

Product

Glucose transporter GLUT5 Antibody

Description

Affinity Purified Solute carrier family 2, facilitated glucose transporter member 5 Antibody

Verified Applications

ELISA, IHC-Fr, IHC-P, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide corresponding to C terminal amino acids 490-500 of Human Glucose Transporter 5 GLUT5. A cysteine residue was included at the N-terminus of the peptide to accommodate KLH conjugation.

Sequence:

ELKEPPVTSEQ

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.7 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunoprecipitation

1:200

Western Blot

1:1,000

Protein

Uniprot #

P22732

Overview

Cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter.

Molecular Function

fructose transmembrane transporter activity

Subcellular Location

Cell membrane, Membrane

Expression

Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue.

Structure

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Alternative Nomenclature

Facilitated glucose transporter member 5 antibody

Fructose transporter antibody

Glucose transporte, kidney antibody

glucose transporter like protein 5 antibody

GLUT5 antibody

SLC2A5 antibody

small intestine antibody

Solute carrier family 2 antibody

General Information

Product

Glucose transporter GLUT5 Antibody

Description

Affinity Purified Solute carrier family 2 , facilitated glucose transporter member 5 Antibody

Verified Applications

ELISA, IP, WB

Species Cross Reactivity

Chimpanzee, Human, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on human GLUT 5 protein.

Accession #

NCBI:  XP_060424.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.7 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunoprecipitation

1:200

Western Blot

1:1,000

Protein

Uniprot #

P22732

Overview

Cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter.

Molecular Function

fructose transmembrane transporter activity

Subcellular Location

Cell membrane, Membrane

Expression

Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue.

Structure

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Alternative Nomenclature

Facilitated glucose transporter member 5 antibody

Fructose transporter antibody

Glucose transporte, kidney antibody

glucose transporter like protein 5 antibody

GLUT5 antibody

SLC2A5 antibody

small intestine antibody

Solute carrier family 2 antibody

General Information

Product

Glucose transporter GLUT2 Antibody

Description

Affinity Purified Solute carrier family 2 glucose transporter member 2 Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human GLUT2 protein.

Accession #

NCBI:  NP_112474.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:100

DB

1:8,000

ELISA

1:8,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P14246

Overview

Facilitative glucose transporter

Molecular Function

glucose transmembrane transporter activity

Subcellular Location

Membrane

Expression

In embryo, expressed in endoderm layer of yolk sac and liver primordium

Structure

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Alternative Nomenclature

liver antibody

Glucose Transporter 2 antibody

Glucose transporter type 2 liver antibody

Glucose transporter, liver/islet antibody

GLUT2 antibody

GTT2 antibody

SLC2A2 antibody

Solute carrier family 2 (facilitated glucose transporter) member 2 antibody