General Information

Product

GPIP137 Antibody

Description

Affinity Purified Caprin-1 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 200-250 on human Caprin 1 protein.

Accession #

NCBI: NP_976240

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.54 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q14444

Overview

Involved in transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types.

Molecular Function

RNA-binding; Differentiation

Subcellular Location

Cytoplasm; Cell projection

Expression

Ubiquitous

Structure

May form homomultimers.  Binds with several mRNAs.  Directly interacts with G3BP1 in cytoplasmic RNA granules.

Alternative Nomenclature

Cell cycle-associated protein 1 antibody

GPI-anchored protein p137 antibody

M11S1 antibody

Membrane component chromosome 11 surface marker 1 antibody

RNA granule protein 105 antibody

General Information

Product

EFEMP1 Antibody

Description

Affinity Purified EGF-containing fibulin-like extracellular matrix protein 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic cyclic peptide corresponding to N terminal amino acids 25-42 of Human EFEMP1, peptide was covalently modified.

Sequence:

TYTQCTDGYEWDPVRQQC

Accession #

NCBI: XP_005264262.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500. Predicted molecular weight 60 kDa

Protein

Uniprot #

UPI000387D485

Overview

Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.

Molecular Function

Calcium

Subcellular Location

Secreted; Extracellular space

Expression

In the eye, associated with photoreceptor outer and inner segment regions, the nerve fiber layer, outer nuclear layer and inner and outer plexiform layers of the retina.

Structure

Interacts with ECM1. Interacts with TIMP3.

Alternative Nomenclature

DHRD antibody

Doyne honeycomb retinal degeneration antibody

DRAD antibody

EFEMP 1 antibody

Epidermal growth factor containing fibulin like extracellular matrix protein 1 antibody

FBLN3 antibody

Fibrillin like antibody

FIBULIN 3 antibody

FLJ35535 antibody

Heat shock 70 KD protein 1 antibody

MGC111353 antibody

MLVT antibody

T16 protein antibody

General Information

Product

Eprhin Receptor A4 Antibody Affinity Purified

Description

Affinity Purified Ephrin type-A receptor 4 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse

Immunogen

Synthetic peptide taken within amino acid region 550-650 on human EphA R4 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q03137

Overview

Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous, it has the unique property among Eph receptors to bind and to be physiologically activated by both GPI-anchored ephrin-A and transmembrane ephrin-B ligands including EFNA1 and EFNB3. Upon activation by ephrin ligands, modulates cell morphology and integrin-dependent cell adhesion through regulation of the Rac, Rap and Rho GTPases activity. Plays an important role in the development of the nervous system controlling different steps of axonal guidance including the establishment of the corticospinal projections. May also control the segregation of motor and sensory axons during neuromuscular circuit development. In addition to its role in axonal guidance plays a role in synaptic plasticity. Activated by EFNA1 phosphorylates CDK5 at 'Tyr-15' which in turn phosphorylates NGEF regulating RHOA and dendritic spine morphogenesis. In the nervous system, plays also a role in repair after injury preventing axonal regeneration and in angiogenesis playing a role in central nervous system vascular formation. Additionally, its promiscuity makes it available to participate in a variety of cell-cell signaling regulating for instance the development of the thymic epithelium.

Molecular Function

ATP-binding, Nucleotide-binding

Subcellular Location

Cell membrane; Single-pass type I membrane protein

Expression

Highest expression in the adult brain and retina and also detectable in kidney, lung, skeletal muscle and thymus. Not detected in heart and liver.

Structure

Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses. Interacts (phosphorylated at position Tyr-602) with FYN. Interacts (via

Alternative Nomenclature

Cek 8 antibody

EK8 antibody

eph receptor a4 antibody

EPH-like kinase 8 antibody

EphA4 antibody

Ephrin receptor Eph A4 antibody

hEK8 antibody

Receptor protein tyrosine kinase HEK 8 antibody

Sek 1 antibody

SEK antibody

TYRO 1 protein tyrosine kinase antibody

Tyrosine-protein kinase receptor SEK antibody

General Information

Product

Ephrin Receptor A7 Antibody

Description

Affinity Purified EPHA7 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding taken within amino acid region 500-550 on human Ephrin type-A receptor 7 protein.

Accession #

NCBI:  NP_004431

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q15375

Overview

Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. 

Molecular Function

Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase

Subcellular Location

Cell membrane, Single-pass type 1 membrane protein

Expression

Widely Expressed

Structure

Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses. Interacts (via PDZ-binding motif) with GRIP1 and PICK.

Alternative Nomenclature

Cek 11 

Developmental kinase 1 

EBK 

EHK3 

EK11 

Embryonic brain kinase 

Eph homology kinase 3 

Eph receptor A7 

EPH-like kinase 11 

EphA7 

Ephrin type-A receptor 7 

hEK11 

MDK 1 

Receptor protein tyrosine kinase HEK 11 

Tyrosine protein kinase receptor EHK 3 

General Information

Product

Eprhin Receptor A6 Antibody Affinity Purified

Description

Affinity Purified Ephrin type-A receptor 6 isoform A Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 800-900 on human EphA R6 protein.

Accession #

NCBI:  NP_001073917

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

B3KS12

Overview

Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).

Molecular Function

ATP-binding, Nucleotide-binding

Subcellular Location

Membrane; Single-pass type I membrane protein

Expression

Expressed in brain and testis.

Structure

Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses (By similarity).

Alternative Nomenclature

Ehk 2 antibody

EPH homology kinase 2 antibody

Eph Receptor A6 antibody

ephrin receptor EphA6 antibody

Hek12 antibody

General Information

Product

Eprhin Receptor A5 Antibody Affinity Purified

Description

Affinity Purified Ephrin Type-1 Receptor isoform a Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 600-700 on human EphA R5 protein.

Accession #

NCBI:  NP_004430

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P54756

Overview

Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity).

Molecular Function

ATP-binding, Nucleotide-binding

Subcellular Location

Membrane; Single-pass type I membrane protein

Expression

Almost exclusively expressed in the nervous system in cortical neurons, cerebellar Purkinje cells and pyramidal neurons within the cortex and hippocampus. Display an increasing gradient of expression from the forebrain to hindbrain and spinal cord.

Structure

Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses (By similarity).

Alternative Nomenclature

Brain-specific kinase antibody

bsk antibody

CEK 7 antibody

Eck like sequence 1 antibody

EHK 1 antibody

EK7 antibody

Els 1 antibody

Eph homology kinase 1 antibody

EPH-like kinase 7 antibody

EphA5 antibody

Ephrin type-A receptor 5 antibody

HEK 7 antibody

Rek 7 antibody

TYRO 4 antibody

Tyrosine protein kinase receptor EHK 1 antibody

General Information

Product

Eprhin Receptor B1 Antibody

Description

Affinity Purified Ephrin type-B receptor 1 isoform 1 Antibody

Verified Applications

ELISA, IHC, IP ,WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 850-900 on mouse Eph BR1 protein.

Accession #

NCBI:  NP_775623

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.58 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:750

Protein

Uniprot #

Q8CBF3

Overview

Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Cognate/functional ephrin ligands for this receptor include EFNB1, EFNB2 and EFNB3. During nervous system development, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline. This probably requires repulsive interaction with EFNB2. In the adult nervous system together with EFNB3, regulates chemotaxis, proliferation and polarity of the hippocampus neural progenitors. In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation. May also regulate angiogenesis. More generally, may play a role in targeted cell migration and adhesion. Upon activation by EFNB1 and probably other ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively.

Molecular Function

ATP-binding, Nucleotide-binding

Subcellular Location

Cell membrane; Single-pass type I membrane protein; Early endosome membrane; Dendrite

Expression

Expressed in neural stem and progenitor cells in the dentate gyrus.

Structure

Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses. Interacts with EPHB6; transphosphorylates EPHB6 to form an active signaling complex. Interacts with PICK1. Interacts (through Tyr-594) with NCK1 (via SH2 domain); activates the JUN cascade to regulate cell adhesion. Then ligand-activated form interacts (through Tyr-928) with GRB7 and GRB10 (via SH2 domains). The ligand-activated form interacts (through Tyr-928) with GRB7 and GRB10 (via SH2 domain). Interacts with GRB2, SHC1 and SRC; activates the MAPK/ERK cascade to regulate cell migration. Interacts with CBL; regulates receptor degradation through ubiquitination. Interacts with ACP1.

Alternative Nomenclature

Cek 6 antibody

EK6 antibody

ELK antibody

Elkh antibody

Eph tyrosine kinase 2 antibody

EPH-like kinase 6 antibody

EPH2 antibody

EphB1 antibody

Ephrin receptor Eph B1 precursor antibody

Ephrin type B receptor 1 antibody

EPHT2 antibody

HEK 6 antibody

NET antibody

Neuronally expressed EPH related tyrosine kinase antibody

Tyrosine-protein kinase receptor EPH-2 antibody

General Information

Product

FGFR1 Antibody

Description

Affinity Purified Fibroblast Growth Factor Receptor 1 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Rat

Immunogen

Synthetic peptide taken within amino acid region 640-690 on human basic fibroblast growth factor receptor protein 1.

Accession #

GenBank: AAA75007.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P11362

Overview

Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription. FGFR1 signaling is down-regulated by IL17RD/SEF, and by FGFR1 ubiquitination, internalization and degradation.

Molecular Function

ATP-binding; Fibroblast growth factor binding; Heparin binding; Protein Tyrosine Kinase activity

Subcellular Location

Cell membrane; Single-pass type I membrane protein. Nucleus. Cytoplasm › cytosol. Cytoplasmic vesicle

Expression

Detected in astrocytoma, neuroblastoma and adrenal cortex cell lines. Some isoforms are detected in foreskin fibroblast cell lines, however isoform 17, isoform 18 and isoform 19 are not detected in these cells.

Structure

Monomer. Homodimer after ligand binding. Interacts predominantly with FGF1 and FGF2, but can also interact with FGF3, FGF4, FGF5, FGF6, FGF8, FGF10, FGF19, FGF21, FGF22 and FGF23 (in vitro). Ligand specificity is determined by tissue-specific expression of isoforms, and differences in the third Ig-like domain are crucial for ligand specificity. Affinity for fibroblast growth factors (FGFs) is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Likewise, KLB increases the affinity for FGF19, FGF21 and FGF23. Interacts (phosphorylated on Tyr-766) with PLCG1 (via SH2 domains). Interacts with FRS2. Interacts (via C-terminus) with NEDD4 (via WW3 domain). Interacts with KL (By similarity). Interacts with SHB (via SH2 domain) and GRB10. Interacts with KAL1; this interaction does not interfere with FGF2-binding to FGFR1, but prevents binding of heparin-bound FGF2. Interacts with SOX2 and SOX3.

Alternative Nomenclature

Basic fibroblast growth factor receptor 1 antibody

bFGF R antibody

C FGR antibody

CD 331 antibody

CEK antibody

FGFBR antibody

FGFR 1 antibody

Fibroblast growth factor receptor 1 antibody

FLG antibody

FLG protein antibody

FLT 2 antibody

FMS like tyrosine kinase 2 antibody

Fms related tyrosine kinase 2 Pfeiffer syndrome antibody

Fms-like tyrosine kinase 2 antibody

HBGFR antibody

Heparin binding growth factor receptor antibody

HH2 antibody

HRTFDS antibody

Hydroxyaryl protein kinase antibody

KAL 2 antibody

MFR antibody

N sam tyrosine kinase antibody

N-SAM antibody

OGD antibody

Proto-oncogene c-Fgr antibody

Tyrosylprotein kinase antibody

General Information

Product

Phospho-FGFR1 Antibody

Description

Affinity Purified Phospho-Fibroblast Growth Factor Receptor 1 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Rat

Immunogen

Synthetic peptide taken within amino acid region 640-690 on human basic fibroblast growth factor receptor protein 1.

Accession #

GenBank: AAA75007.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P11362

Overview

Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription. FGFR1 signaling is down-regulated by IL17RD/SEF, and by FGFR1 ubiquitination, internalization and degradation.

Molecular Function

ATP-binding; Fibroblast growth factor binding; Heparin binding; Protein Tyrosine Kinase activity

Subcellular Location

Cell membrane; Single-pass type I membrane protein. Nucleus. Cytoplasm › cytosol. Cytoplasmic vesicle

Expression

Detected in astrocytoma, neuroblastoma and adrenal cortex cell lines. Some isoforms are detected in foreskin fibroblast cell lines, however isoform 17, isoform 18 and isoform 19 are not detected in these cells.

Structure

Monomer. Homodimer after ligand binding. Interacts predominantly with FGF1 and FGF2, but can also interact with FGF3, FGF4, FGF5, FGF6, FGF8, FGF10, FGF19, FGF21, FGF22 and FGF23 (in vitro). Ligand specificity is determined by tissue-specific expression of isoforms, and differences in the third Ig-like domain are crucial for ligand specificity. Affinity for fibroblast growth factors (FGFs) is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Likewise, KLB increases the affinity for FGF19, FGF21 and FGF23. Interacts (phosphorylated on Tyr-766) with PLCG1 (via SH2 domains). Interacts with FRS2. Interacts (via C-terminus) with NEDD4 (via WW3 domain). Interacts with KL (By similarity). Interacts with SHB (via SH2 domain) and GRB10. Interacts with KAL1; this interaction does not interfere with FGF2-binding to FGFR1, but prevents binding of heparin-bound FGF2. Interacts with SOX2 and SOX3.

Alternative Nomenclature

Basic fibroblast growth factor receptor 1 antibody

bFGF R antibody

C FGR antibody

CD 331 antibody

CEK antibody

FGFBR antibody

FGFR 1 antibody

Fibroblast growth factor receptor 1 antibody

FLG antibody

FLG protein antibody

FLT 2 antibody

FMS like tyrosine kinase 2 antibody

Fms related tyrosine kinase 2 Pfeiffer syndrome antibody

Fms-like tyrosine kinase 2 antibody

HBGFR antibody

Heparin binding growth factor receptor antibody

HH2 antibody

HRTFDS antibody

Hydroxyaryl protein kinase antibody

KAL 2 antibody

MFR antibody

N sam tyrosine kinase antibody

N-SAM antibody

OGD antibody

Proto-oncogene c-Fgr antibody

Tyrosylprotein kinase antibody

General Information

Product

FSH Antibody

Description

Affinity Purified Follicle stimulating hormone Antibody

Verified Applications

CM, ELISA, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-60 on human FSH protein.

Accession #

GenBank: ABD84005

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.71 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

Dot Blot

1:50,000

ELISA

1:50,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Western Blot

1:500

Protein

Uniprot #

Q1W658

Overview

Binds to activin directly and serves as an activin antagonist.  Acts as a specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone.

Subcellular Location

Secreted

Structure

Monomer

Alternative Nomenclature

Follicle stimulating hormone receptor isoform 1 antibody

Follitropin receptor antibody

FSH receptor antibody

FSH-R antibody

FSHRO antibody

LGR1 antibody

MGC141667 antibody

MGC141668 antibody

ODG1 antibody

ovarian dysgenesis 1 antibody